Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRN | P28799 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 7/20 | 0.32 |
| ▸ | MMP3 | P08254 | 6/20 | 0.32 |
| ▸ | MMP9 | P14780 | 6/20 | 0.32 |
| ▸ | MMP2 | P08253 | 6/20 | 0.32 |
| ▸ | MMP8 | P22894 | 4/20 | 0.32 |
| ▸ | MMP13 | P45452 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23613012 | 0.83 | MLYCD (0.42) | MLYCDALDH1A1CTSLCTSBCTSS | |
| SCHEMBL18287169 | 0.79 | MLYCD (0.39) | MLYCDALDH1A1CTSKMEN1LMNA | |
| SCHEMBL18287166 | 0.78 | ALDH1A1 (0.41) | ALDH1A1CTSKMEN1LMNAKMT2A | |
| SCHEMBL12204111 | 0.77 | MLYCD (0.53) | MLYCDALDH1A1CA1CA2CTSS | |
| SCHEMBL25134681 | 0.77 | MLYCD (0.53) | MLYCDALDH1A1CA1CA2CTSS | |
| SCHEMBL19021911 | 0.73 | CA1 (0.58) | CA1CA2CA7CTSLCTSB | |
| SCHEMBL902049 | 0.73 | CA1 (0.58) | CA1CA2CA7CTSLCTSB | |
| SCHEMBL20370208 | 0.73 | MLYCD (0.36) | MLYCDALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL18287160 | 0.72 | MMP1 (0.42) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL16351261 | 0.72 | ALDH1A1 (0.50) | MLYCDALDH1A1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10981862-B2 | Physiological cooling compounds | SYMRISE, INC. (US) | 2021-04-20 | — | — | US | disclosed |
| US-10173966-B2 | Physiological cooling compounds | SYMRISE, INC. (US) | 2019-01-08 | — | — | US | disclosed |
| US-20180179147-A1 | PHYSIOLOGICAL COOLING COMPOUNDS | SYMRISE, INC. | 2018-06-28 | — | — | US | disclosed |
| US-20180179147-A1 | PHYSIOLOGICAL COOLING COMPOUNDS | SYMRISE, INC. | 2018-06-28 | — | — | US | disclosed |
| US-20160355463-A1 | PHYSIOLOGICAL COOLING COMPOUNDS | SYMRISE, INC. | 2016-12-08 | — | — | US | disclosed |
| US-20160355463-A1 | PHYSIOLOGICAL COOLING COMPOUNDS | SYMRISE, INC. | 2016-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10981862-B2 | Physiological cooling compounds | TAS2R8, TAS2R3, TAS2R1 | MLYCD 670/4885ALDH1A1 1970/4885CA1 3222/4885 |
| US-10173966-B2 | Physiological cooling compounds | TAS2R8, TAS2R3, TAS2R1 | MLYCD 670/4885ALDH1A1 1970/4885CA1 3222/4885 |
| US-20160355463-A1 | PHYSIOLOGICAL COOLING COMPOUNDS | TAS2R8, TAS2R3, TAS2R1 | MLYCD 670/4885ALDH1A1 1970/4885CA1 3222/4885 |
| US-20180179147-A1 | PHYSIOLOGICAL COOLING COMPOUNDS | TAS2R8, TAS2R3, TAS2R1 | MLYCD 670/4885ALDH1A1 1970/4885CA1 3222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.