Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18287167 | 0.87 | MLYCD (0.46) | KMT2ACTSKTAS1R3TAS1R1MEN1 | |
| SCHEMBL23613007 | 0.83 | ALDH1A1 (0.43) | ALDH1A1POLBHPGDKMT2ANPC1 | |
| SCHEMBL18287169 | 0.81 | MLYCD (0.39) | ALDH1A1KMT2ALMNACTSKTAS1R3 | |
| SCHEMBL15895098 | 0.80 | RIPK1 (0.42) | ALDH1A1POLBHPGDKMT2ANPC1 | |
| SCHEMBL23175981 | 0.80 | RIPK1 (0.42) | ALDH1A1POLBHPGDKMT2ANPC1 | |
| SCHEMBL23175980 | 0.78 | ALDH1A1 (0.40) | ALDH1A1POLBHPGDKMT2ANPC1 | |
| SCHEMBL18287165 | 0.78 | MLYCD (0.40) | ALDH1A1KMT2ALMNACTSKMEN1 | |
| SCHEMBL7230655 | 0.78 | ALDH1A1 (0.46) | ALDH1A1POLBHPGDKMT2ANPC1 | |
| SCHEMBL22403767 | 0.77 | ALDH1A1 (0.39) | ALDH1A1POLBHPGDKMT2ANPC1 | |
| SCHEMBL18287160 | 0.75 | MMP1 (0.42) | POLBLMNASMN1; SMN2CTSKPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10981862-B2 | Physiological cooling compounds | SYMRISE, INC. (US) | 2021-04-20 | — | — | US | disclosed |
| US-10173966-B2 | Physiological cooling compounds | SYMRISE, INC. (US) | 2019-01-08 | — | — | US | disclosed |
| US-20180179147-A1 | PHYSIOLOGICAL COOLING COMPOUNDS | SYMRISE, INC. | 2018-06-28 | — | — | US | disclosed |
| US-20180179147-A1 | PHYSIOLOGICAL COOLING COMPOUNDS | SYMRISE, INC. | 2018-06-28 | — | — | US | disclosed |
| US-20160355463-A1 | PHYSIOLOGICAL COOLING COMPOUNDS | SYMRISE, INC. | 2016-12-08 | — | — | US | disclosed |
| US-20160355463-A1 | PHYSIOLOGICAL COOLING COMPOUNDS | SYMRISE, INC. | 2016-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10981862-B2 | Physiological cooling compounds | TAS2R8, TAS2R3, TAS2R1 | ALDH1A1 1970/4885POLB 2636/4885HPGD 3247/4885 |
| US-10173966-B2 | Physiological cooling compounds | TAS2R8, TAS2R3, TAS2R1 | ALDH1A1 1970/4885POLB 2636/4885HPGD 3247/4885 |
| US-20160355463-A1 | PHYSIOLOGICAL COOLING COMPOUNDS | TAS2R8, TAS2R3, TAS2R1 | ALDH1A1 1970/4885POLB 2636/4885HPGD 3247/4885 |
| US-20180179147-A1 | PHYSIOLOGICAL COOLING COMPOUNDS | TAS2R8, TAS2R3, TAS2R1 | ALDH1A1 1970/4885POLB 2636/4885HPGD 3247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.