Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10126573 | 0.72 | APEX1 (0.45) | GAATSHRKMT2AKDM4EALDH1A1 | |
| SCHEMBL19104605 | 0.72 | APEX1 (0.45) | GAATSHRKMT2AKDM4EALDH1A1 | |
| SCHEMBL1714853 | 0.71 | CASP6 (0.35) | TBXA2RKMT2AKDM4EALDH1A1MEN1 | |
| Bromide SCHEMBL28558479 | 0.69 | TSHR (0.43) | GAATSHRPPARGKMT2AAKR1B1 | |
| SCHEMBL7602622 | 0.68 | ALDH1A1 (0.40) | GAATSHRPPARGKMT2AKDM4E | |
| SCHEMBL10111020 | 0.68 | GPR84 (0.46) | TSHRPPARGKMT2AAKR1B1ALDH1A1 | |
| SCHEMBL12012034 | 0.68 | TSHR (0.38) | GAATSHRPPARGKMT2AKDM4E | |
| P-Xylene SCHEMBL36101 | 0.67 | TSHR (0.60) | TSHRPPARGKMT2AALDH1A1LMNA | |
| Sebacic Acid SCHEMBL36102 | 0.67 | TSHR (0.60) | TSHRPPARGKMT2AALDH1A1LMNA | |
| Azelaic Acid SCHEMBL3807504 | 0.67 | TSHR (0.60) | TSHRPPARGKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160356681-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | Life Technologies Corporation | 2016-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160356681-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | IK, CBR3, DRD5 | GAA 4104/4885TSHR 2666/4885TBXA2R 3668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.