Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18292235 | 0.95 | ALDH1A1 (0.33) | ALDH1A1HPGDSMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL18288656 | 0.88 | ALOX15 (0.32) | ALDH1A1HPGDSMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL18292237 | 0.86 | SMN1; SMN2 (0.47) | ALDH1A1HPGDSMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL18288709 | 0.81 | ALDH1A1 (0.43) | ALDH1A1HPGDSMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL2115608 | 0.81 | HCAR2 (0.47) | ALDH1A1HPGDSMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL2609715 | 0.81 | SMN1; SMN2 (0.43) | ALDH1A1HPGDSMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL2609712 | 0.81 | SMN1; SMN2 (0.43) | ALDH1A1HPGDSMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL2115607 | 0.81 | HCAR2 (0.47) | ALDH1A1HPGDSMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL29257694 | 0.74 | GAA (0.36) | ALDH1A1SMN1; SMN2GAAKDM4EKMT2A | |
| SCHEMBL18288694 | 0.73 | LMNA (0.38) | ALDH1A1HPGDSMN1; SMN2ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160355464-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | Nguyen, Mark Quang (US) | 2016-12-08 | — | — | US | disclosed |
| US-20160355464-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | Nguyen, Mark Quang (US) | 2016-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160355464-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | FH, FPGS, APC | ALDH1A1 1949/4885HPGD 113/4885SMN1; SMN2 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.