Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 1/20 | 0.50 |
| ▸ | SOD1 | P00441 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 5/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 2/20 | 0.36 |
| ▸ | PNLIP | P16233 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | JUN | P05412 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GLI1 | P08151 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sugiol SCHEMBL17407685 | 0.69 | SOD1 (0.58) | KARS1SOD1FDPSGGPS1PTGES | |
| Sugiol SCHEMBL1086916 | 0.69 | SOD1 (0.58) | KARS1SOD1FDPSGGPS1PTGES | |
| Sugiol SCHEMBL28605319 | 0.69 | SOD1 (0.58) | KARS1SOD1FDPSGGPS1PTGES | |
| Ferruginol SCHEMBL155580 | 0.68 | KARS1 (0.73) | KARS1FDPSGGPS1PTGESPNLIP | |
| Ferruginol SCHEMBL5315022 | 0.68 | KARS1 (0.73) | KARS1FDPSGGPS1PTGESPNLIP | |
| Ferruginol SCHEMBL13423521 | 0.68 | KARS1 (0.73) | KARS1FDPSGGPS1PTGESPNLIP | |
| SCHEMBL13532266 | 0.68 | SOD1 (0.52) | KARS1SOD1FDPSGGPS1PTGES | |
| SCHEMBL21360678 | 0.68 | OPRM1 (0.65) | KARS1SOD1FDPSGGPS1NR1I2 | |
| SCHEMBL21360690 | 0.68 | OPRM1 (0.65) | KARS1SOD1FDPSGGPS1NR1I2 | |
| SCHEMBL18290200 | 0.68 | SOD1 (0.76) | KARS1SOD1FDPSGGPS1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016192631-A1 | ABIETANE-TYPE DITERPENE COMPOUND HAVING LIPID-LOWERING ACTIVITY, METHOD FOR PREPARING SAME, AND USE OF SAME | 中国科学院上海药物研究所 | 2016-12-08 | — | — | WO | disclosed |