Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6032869 | 0.80 | CYP2C19 (0.50) | F2BCHECTSDHRH3CYP2C19 | |
| SCHEMBL1678422 | 0.77 | ADRA2B (0.49) | ADRA2BF2FDPSCTSDLOXL2 | |
| SCHEMBL23015247 | 0.74 | KDM4C (0.47) | ADRA2BF2FDPSCTSDLOXL2 | |
| SCHEMBL5157848 | 0.72 | APP (0.44) | HRH3CYP2C19 | |
| Hydrochloric Acid SCHEMBL5456304 | 0.71 | APP (0.43) | HRH3CYP2C19 | |
| SCHEMBL27371676 | 0.69 | LMNA (0.43) | F2CARM1PRMT6PRMT8LOXL2 | |
| SCHEMBL14985489 | 0.69 | CTSD (0.46) | ADRA2BF2FDPSBCHECTSD | |
| SCHEMBL7054279 | 0.69 | LIMK1 (0.51) | ADRA2BF2FDPSCTSDKCNH2 | |
| SCHEMBL19361365 | 0.68 | MAPT (0.38) | — | |
| SCHEMBL31041802 | 0.67 | CA1 (0.36) | CARM1PRMT6PRMT8HRH3CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016196393-A2 | AUTOPHAGY-INHIBITING COMPOUNDS AND USES THEREOF | PRESAGE BIOSCIENCES, INC. (US) | 2016-12-08 | — | — | WO | disclosed |