SCHEMBL676468

SCHEMBL676468

C=CCc1ccc(C=O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
CYP3A4 P08684 2/20 0.48
TP53 P04637 1/20 0.48
ALOX15 P16050 1/20 0.48
TSHR P16473 1/20 0.48
ALOX12 P18054 1/20 0.48
XDH P47989 1/20 0.43
CYP2A6 P11509 3/20 0.42
HSD17B10 Q99714 2/20 0.42
ALDH5A1 P51649 1/20 0.42
ABAT P80404 1/20 0.42
MAPT P10636 3/20 0.42
HPGD P15428 2/20 0.42
PPARG P37231 2/20 0.42
PPARD Q03181 2/20 0.42
KDM4E B2RXH2 2/20 0.42
MEN1 O00255 1/20 0.42
ALDH2 P05091 1/20 0.42
GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9239401 0.94 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15
SCHEMBL15822354 0.88 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15
SCHEMBL4745365 0.82 CYP2A6 (0.48) ALDH1A1SMN1; SMN2CYP2A6HSD17B10ALDH5A1
SCHEMBL173301 0.82 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15
SCHEMBL8669516 0.80 CYP2A6 (0.46) ALDH1A1SMN1; SMN2CYP2A6HSD17B10ALDH5A1
SCHEMBL278055 0.80 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15
SCHEMBL182937 0.80 RAB9A (0.45) ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15
SCHEMBL10693711 0.79 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15
Bromide SCHEMBL8645583 0.79 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15
Phosphine SCHEMBL28908227 0.79 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119239161-A Thin offset cold stamping material and preparation process thereof 东莞光群雷射科技有限公司 2025-01-03 CN claimed
CN-114534707-B Alkenyl benzene compound C=C isomerization catalyst and preparation method and application thereof 中国科学院理化技术研究所 2024-03-01 CN claimed
CN-111217862-B Preparation method of 4-aryl-6-ferrocenyl-3, 4-dihydropyrimidine-2 (1H) -ketone 陕西科技大学 2023-01-31 CN claimed
CN-111217862-A Preparation method of 4-aryl-6-ferrocenyl-3, 4-dihydropyrimidine-2 (1H) -ketone 陕西科技大学 2020-06-02 CN claimed
EP-2970073-B1 PRODUCTION OF PARA-PROPYLBENZALDEHYDE ALBEMARLE CORP (US) 2019-10-30 EP claimed
CN-105143166-B Production of p-propylbenzaldehyde 阿尔比马尔公司 2017-09-15 CN claimed
US-9567278-B2 Production of para-propylbenzaldehyde ALBEMARLE CORPORATION (US) 2017-02-14 US claimed
EP-2970073-A2 PRODUCTION OF PARA-PROPYLBENZALDEHYDE Albemarle Corporation (US) 2016-01-20 EP claimed
US-20150368175-A1 PRODUCTION OF PARA-PROPYLBENZALDEHYDE W.R. GRACE & CO.-CONN 2015-12-24 US claimed
CN-105143166-A Production of p-propylbenzaldehyde ALBEMARLE CORP 2015-12-09 CN claimed
WO-2007071743-A1 IMPROVED PROCESS FOR THE PREPARATION OF THE SALTS OF 4-(BENZIMIDAZOLYLMETHYLAMINO)-BENZAMIDES BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-06-28 WO claimed
US-20060287303-A1 Modulators of muscarinic receptors VERTEX PHARMACEUTICALS INCORPORATED 2006-12-21 US claimed
WO-2006058294-A2 MODULATORS OF MUSCARINIC RECEPTORS VERTEX PHARMACEUTICALS INCORPORATED (US) 2006-06-01 WO claimed
US-7022862-B2 Scalable synthesis of dipyrromethanes NORTH CAROLINA STATE UNIVERSITY (US) 2006-04-04 US claimed
US-20050038262-A1 aldehyde-pyrrole catalytic condensation leading to dipyrromethanes as a crystalline solid or as intermediates used for making porphyrin compounds; non-aqueous process NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-02-17 US claimed
US-4868241-A POLYVINYL ALCOHOL MODIFIED WITH BENZOIC ACID DERIVATIVE AMERICAN CYANAMID COMPANY (US) 1989-09-19 US claimed
EP-0231922-A2 Electron beam and X-ray resists AMERICAN CYANAMID COMPANY (US) 1987-08-12 EP claimed
US-4619788-A HEXASUBSTITUTED TRIBENZOCYCLONONATRIENE MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) 1986-10-28 US claimed
US-4582903-A Synthesis of unsaturated hydantoins with an inexpensive catalyst STAUFFER CHEMICAL COMPANY (US) 1986-04-15 US claimed
US-4345072-A Process for the production of 5-arylidene hydantoins (B) DEGUSSA AG (DE) 1982-08-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038262-A1 aldehyde-pyrrole catalytic condensation leading to dipyrromethanes as a crystalline solid or as intermediates used for making porphyrin compounds; non-aqueous process PPOX, DAO, DDO ALDH1A1 72/4885SMN1; SMN2 4585/4885CYP3A4 257/4885
US-20060287303-A1 Modulators of muscarinic receptors CHRM3, CHRM5, CHRM2 ALDH1A1 2356/4885SMN1; SMN2 3349/4885CYP3A4 1260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.