Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.36 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | IDH1 | O75874 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 2/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18308511 | 0.83 | MRGPRX4 (0.40) | MAPT | |
| SCHEMBL18308334 | 0.82 | MAPT (0.33) | MAPT | |
| SCHEMBL18308342 | 0.82 | PDE2A (0.36) | PLK1MAPTMET | |
| SCHEMBL18308508 | 0.81 | KIT (0.38) | PLK1PRKDCMET | |
| SCHEMBL18308506 | 0.80 | ALDH1A1 (0.37) | PLK1MAPT | |
| SCHEMBL18308550 | 0.79 | HPGDS (0.31) | — | |
| SCHEMBL18308509 | 0.78 | PLK1 (0.38) | PLK1MAPTPRKDC | |
| SCHEMBL18308538 | 0.77 | VCP (0.32) | PLK1 | |
| SCHEMBL18308373 | 0.71 | CSF1R (0.37) | IDH1MAPT | |
| SCHEMBL18308378 | 0.66 | BRD4 (0.36) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016199943-A1 | HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-12-15 | — | — | WO | disclosed |