Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 2/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18308331 | 0.90 | RECQL (0.35) | MAPTAPLNRALDH1A1LMNA | |
| SCHEMBL18308334 | 0.88 | MAPT (0.33) | MAPT | |
| SCHEMBL18308329 | 0.87 | PLK1 (0.36) | PLK1MAPTIDH1 | |
| SCHEMBL18308550 | 0.86 | HPGDS (0.31) | — | |
| SCHEMBL18308342 | 0.85 | PDE2A (0.36) | PLK1MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL18308511 | 0.85 | MRGPRX4 (0.40) | MAPTNPSR1 | |
| SCHEMBL18308506 | 0.85 | ALDH1A1 (0.37) | PLK1MAPTAPLNRKDM4EALDH1A1 | |
| SCHEMBL18308508 | 0.85 | KIT (0.38) | PLK1 | |
| SCHEMBL18308333 | 0.84 | LCK (0.32) | MAPT | |
| SCHEMBL18308505 | 0.84 | MAPT (0.34) | MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016199943-A1 | HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-12-15 | — | — | WO | disclosed |