Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.35 |
| ▸ | IDH1 | O75874 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18308537 | 0.94 | MAPT (0.36) | METIDH1MAPTPDGFRBPDGFRA | |
| SCHEMBL18308539 | 0.92 | MET (0.37) | METIDH1MAPTPDGFRBPDGFRA | |
| SCHEMBL18308323 | 0.90 | IDH1 (0.34) | METIDH1MAPT | |
| SCHEMBL18308332 | 0.87 | KIT (0.35) | METIDH1 | |
| SCHEMBL18308344 | 0.86 | KIT (0.36) | METIDH1MAPTGRIN1GRIN2B | |
| SCHEMBL18308334 | 0.86 | MAPT (0.33) | MAPT | |
| SCHEMBL18308511 | 0.85 | MRGPRX4 (0.40) | MAPTPPARG | |
| SCHEMBL18308394 | 0.84 | APLNR (0.33) | METIDH1PPARG | |
| SCHEMBL18308509 | 0.82 | PLK1 (0.38) | MAPTGRIN1GRIN2B | |
| SCHEMBL18308324 | 0.82 | MAPT (0.34) | MAPTPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016199943-A1 | HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-12-15 | — | — | WO | disclosed |