Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 10/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 2/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18308537 | 0.95 | MAPT (0.36) | METMAPTFYNKDM4EUSP2 | |
| SCHEMBL18308541 | 0.92 | MET (0.35) | METMAPTIDH1PDGFRBPDGFRA | |
| SCHEMBL18308504 | 0.91 | MET (0.36) | METKDM4EIDH1PDGFRBPDGFRA | |
| SCHEMBL18308416 | 0.91 | GAA (0.33) | METMAPTKDM4EUSP2ALDH1A1 | |
| SCHEMBL18308323 | 0.90 | IDH1 (0.34) | METMAPTFYNKDM4EALDH1A1 | |
| SCHEMBL18308542 | 0.89 | PLK1 (0.32) | MAPTKDM4EALDH1A1LMNAIDH1 | |
| SCHEMBL18308332 | 0.88 | KIT (0.35) | METALDH1A1TSHRSMN1; SMN2IDH1 | |
| SCHEMBL18308344 | 0.87 | KIT (0.36) | METMAPTKDM4ELMNAIDH1 | |
| SCHEMBL18308511 | 0.85 | MRGPRX4 (0.40) | MAPTSMN1; SMN2 | |
| SCHEMBL18308394 | 0.85 | APLNR (0.33) | METIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016199943-A1 | HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-12-15 | — | — | WO | disclosed |