Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 10/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1831610 | 0.95 | LPAR3 (0.49) | LPAR3LPAR2LPAR1TSHRLPAR5 | |
| SCHEMBL1831267 | 0.91 | THRB (0.39) | LPAR3LPAR2LPAR1ALDH1A1TSHR | |
| SCHEMBL5595272 | 0.89 | THRB (0.38) | LPAR3LPAR2LPAR1ALDH1A1TSHR | |
| SCHEMBL1831246 | 0.89 | THRB (0.38) | LPAR3LPAR2LPAR1ALDH1A1TSHR | |
| SCHEMBL12394927 | 0.84 | LPAR3 (0.41) | LPAR3LPAR2LPAR1ALDH1A1LPAR5 | |
| SCHEMBL5597304 | 0.82 | LPAR3 (0.47) | LPAR3LPAR2LPAR1LPAR5 | |
| SCHEMBL14678815 | 0.82 | ALDH1A1 (0.41) | LPAR3LPAR2LPAR1ALDH1A1TSHR | |
| SCHEMBL9906105 | 0.81 | THRB (0.39) | ALDH1A1TSHRTHRBMAPT | |
| SCHEMBL27477825 | 0.80 | CES2 (0.44) | ALDH1A1TSHRTHRBMAPT | |
| SCHEMBL6474037 | 0.80 | THRB (0.38) | ALDH1A1TSHRTHRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198388-B2 | One-part self-etching, self-priming dental adhesive composition | DENTSPLY INTERNATIONAL INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-8198388-B2 | One-part self-etching, self-priming dental adhesive composition | DENTSPLY INTERNATIONAL INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-8198388-B2 | One-part self-etching, self-priming dental adhesive composition | DENTSPLY INTERNATIONAL INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-20070293642-A1 | One-Part Self-Etching, Self-Priming Dental Adhesive Composition | DENTSPLY DE TREY GMBH (DE) | 2007-12-20 | — | — | US | disclosed |
| US-20070293642-A1 | One-Part Self-Etching, Self-Priming Dental Adhesive Composition | DENTSPLY DE TREY GMBH (DE) | 2007-12-20 | — | — | US | disclosed |
| US-20070293642-A1 | One-Part Self-Etching, Self-Priming Dental Adhesive Composition | DENTSPLY DE TREY GMBH (DE) | 2007-12-20 | — | — | US | disclosed |
| WO-2005063778-A1 | ONE-PART SELF-ETCHING, SELF-PRIMING DENTAL ADHESIVE COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2005-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293642-A1 | One-Part Self-Etching, Self-Priming Dental Adhesive Composition | CAD, ASIC1, PDAP1 | LPAR3 2740/4885LPAR2 2008/4885LPAR1 1057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.