Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPRS1 | P07814 | 2/20 | 0.48 |
| ▸ | HINT1 | P49773 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.45 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18314781 | 0.88 | HINT1 (0.60) | EPRS1HINT1 | |
| SCHEMBL18314780 | 0.88 | HINT1 (0.60) | EPRS1HINT1 | |
| SCHEMBL18314786 | 0.82 | PI4KA (0.55) | EPRS1HINT1RXFP1 | |
| SCHEMBL18314801 | 0.78 | HINT1 (0.62) | EPRS1HINT1ADORA3ADORA2AADORA2B | |
| SCHEMBL18314782 | 0.75 | EPRS1 (0.76) | EPRS1HINT1 | |
| SCHEMBL31533324 | 0.75 | EPRS1 (0.76) | EPRS1HINT1 | |
| SCHEMBL18314805 | 0.75 | POLB (0.48) | EPRS1HINT1STING1 | |
| SCHEMBL18314956 | 0.74 | ADORA3 (0.50) | EPRS1HINT1ADORA3ADORA2B | |
| SCHEMBL18314784 | 0.73 | PI4KA (0.58) | EPRS1HINT1RXFP1 | |
| SCHEMBL29941642 | 0.73 | ADORA3 (0.62) | ADORA3HSP90B1ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016201374-A1 | SULFANIDE ADENOSINE DERIVATIVES AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2016-12-15 | — | — | WO | disclosed |