Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 17/20 | 0.60 |
| ▸ | CA1 | P00915 | 17/20 | 0.60 |
| ▸ | CA2 | P00918 | 17/20 | 0.60 |
| ▸ | CA7 | P43166 | 17/20 | 0.60 |
| ▸ | CA9 | Q16790 | 17/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 17/20 | 0.60 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.56 |
| ▸ | ATXN2 | Q99700 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18315539 | 0.85 | ENPP2 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL14493373 | 0.77 | CA12 (0.87) | CA12CA1CA2CA7CA9 | |
| SCHEMBL18315532 | 0.77 | ENPP2 (0.63) | ENPP2ATXN2 | |
| SCHEMBL23628467 | 0.76 | CA1 (0.63) | CA12CA1CA2CA7CA9 | |
| SCHEMBL18423403 | 0.75 | MGLL (0.63) | — | |
| SCHEMBL17363200 | 0.74 | CA1 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15540387 | 0.73 | ENPP2 (1.00) | CA2ENPP2ATXN2 | |
| SCHEMBL21485402 | 0.72 | CA2 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3570536 | 0.71 | CA12 (0.78) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31650449 | 0.71 | CA12 (0.71) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2861566-B1 | NEW DIAZASPIROCYCLOALKANE AND AZASPIROCYCLOALKANE | HOFFMANN LA ROCHE (CH) | 2016-12-21 | — | — | EP | claimed |