Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30490051 | 1.00 | HTR2A (0.50) | HTR2ASLC6A4SLC6A2SLC6A3HTT | |
| SCHEMBL2000120 | 0.84 | TSHR (0.58) | L3MBTL1TDP1ALDH1A1NPSR1KMT2A | |
| Hydrochloric Acid SCHEMBL4382625 | 0.82 | TSHR (0.56) | L3MBTL1TDP1ALDH1A1NPSR1ALOX12 | |
| SCHEMBL18319346 | 0.81 | HTR2A (0.50) | HTR2ASLC6A4HTTL3MBTL1TDP1 | |
| SCHEMBL30490050 | 0.81 | SLC6A2 (0.46) | SLC6A4SLC6A2SLC6A3HTTL3MBTL1 | |
| SCHEMBL30490056 | 0.81 | HTR2A (0.50) | HTR2ASLC6A4HTTL3MBTL1TDP1 | |
| SCHEMBL30490055 | 0.81 | ALDH1A1 (0.53) | SLC6A4SLC6A2SLC6A3HTTL3MBTL1 | |
| SCHEMBL11158176 | 0.78 | NPSR1 (0.57) | HTR2ASLC6A4HTTL3MBTL1TDP1 | |
| SCHEMBL16296139 | 0.77 | RHEB (0.47) | SLC6A4SLC6A2SLC6A3TDP1ALDH1A1 | |
| SCHEMBL18319356 | 0.77 | CACNA1B (0.49) | L3MBTL1TDP1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3112343-B1 | AMIDE DERIVATIVES | UNIV TOHOKU (JP) | 2023-03-29 | — | — | EP | disclosed |
| US-11040937-B2 | Amide derivative | TOHOKU UNIVERSITY (JP) | 2021-06-22 | — | — | US | disclosed |
| CN-106029632-B | Amide derivatives | 国立大学法人东北大学 | 2019-06-21 | — | — | CN | disclosed |
| EP-3112343-A1 | AMIDE DERIVATIVES | Tohoku University (JP) | 2017-01-04 | — | — | EP | disclosed |
| US-20160368860-A1 | AMIDE DERIVATIVE | TOHOKU UNIVERSITY (JP) | 2016-12-22 | — | — | US | disclosed |
| CN-106029632-A | Amide derivatives | 国立大学法人东北大学 | 2016-10-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160368860-A1 | AMIDE DERIVATIVE | ARG1, PTMS, MLX | HTR2A 4028/4885SLC6A4 2674/4885SLC6A2 2241/4885 |
| US-11040937-B2 | Amide derivative | ARG1, PTMS, MLX | HTR2A 4028/4885SLC6A4 2674/4885SLC6A2 2241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.