Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 5/20 | 0.49 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30490052 | 0.83 | MAPT (0.49) | CACNA1BL3MBTL1ALDH1A1POLBTDP1 | |
| SCHEMBL30490053 | 0.83 | MAPT (0.49) | CACNA1BL3MBTL1ALDH1A1POLBTDP1 | |
| SCHEMBL7410783 | 0.83 | RXFP1 (0.47) | L3MBTL1ALDH1A1POLBTDP1RAB9A | |
| SCHEMBL28638978 | 0.82 | L3MBTL1 (0.52) | CACNA1BL3MBTL1ALDH1A1RAB9AMAPT | |
| SCHEMBL2000120 | 0.80 | TSHR (0.58) | L3MBTL1ALDH1A1POLBTDP1TSHR | |
| Hydrochloric Acid SCHEMBL4382625 | 0.78 | TSHR (0.56) | L3MBTL1ALDH1A1POLBTDP1TSHR | |
| SCHEMBL18319346 | 0.77 | HTR2A (0.50) | L3MBTL1ALDH1A1POLBTDP1MAPT | |
| SCHEMBL30490051 | 0.77 | HTR2A (0.50) | L3MBTL1ALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL18319286 | 0.77 | HTR2A (0.50) | L3MBTL1ALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL30490050 | 0.77 | SLC6A2 (0.46) | L3MBTL1ALDH1A1POLBTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3112343-B1 | AMIDE DERIVATIVES | UNIV TOHOKU (JP) | 2023-03-29 | — | — | EP | disclosed |
| US-11040937-B2 | Amide derivative | TOHOKU UNIVERSITY (JP) | 2021-06-22 | — | — | US | disclosed |
| EP-3112343-A1 | AMIDE DERIVATIVES | Tohoku University (JP) | 2017-01-04 | — | — | EP | disclosed |
| US-20160368860-A1 | AMIDE DERIVATIVE | TOHOKU UNIVERSITY (JP) | 2016-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160368860-A1 | AMIDE DERIVATIVE | ARG1, PTMS, MLX | CACNA1B 2096/4885CACNA1H 3522/4885L3MBTL1 2587/4885 |
| US-11040937-B2 | Amide derivative | ARG1, PTMS, MLX | CACNA1B 2096/4885CACNA1H 3522/4885L3MBTL1 2587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.