SCHEMBL1832020

SCHEMBL1832020

CC(C)c1c(C(N)=O)cccc1C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 1/20 0.44
ALDH1A1 P00352 3/20 0.43
ALOX15 P16050 1/20 0.43
MYC P01106 1/20 0.42
KDM4E B2RXH2 2/20 0.41
HPGD P15428 2/20 0.41
HSD17B10 Q99714 2/20 0.41
G6PD P11413 1/20 0.41
CASP7 P55210 1/20 0.41
CASP6 P55212 1/20 0.41
MMP2 P08253 1/20 0.41
BCAT2 O15382 1/20 0.41
MAPT P10636 2/20 0.41
TSHR P16473 2/20 0.41
HDAC8 Q9BY41 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
KEAP1 Q14145 1/20 0.41
NFE2L2 Q16236 1/20 0.41
PARP1 P09874 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2977145 0.92 IRAK4 (0.50) IRAK4ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL3389839 0.90 ALDH1A1 (0.52) ALDH1A1ALOX15MYCKDM4EHPGD
SCHEMBL5432823 0.81 MMP2 (0.55) ALDH1A1ALOX15MYCKDM4EHPGD
SCHEMBL16592837 0.81 IRAK4 (0.44) IRAK4ALDH1A1MYCKDM4EHPGD
SCHEMBL458410 0.81 IRAK4 (0.44) IRAK4ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL3628076 0.81 IRAK4 (0.44) IRAK4ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL6951207 0.81 KDM4E (0.55) IRAK4ALDH1A1ALOX15KDM4EHPGD
SCHEMBL30797325 0.81 IRAK4 (0.44) IRAK4ALDH1A1KDM4EHPGDHSD17B10
Oxalic Acid SCHEMBL23529511 0.80 IRAK4 (0.41) IRAK4ALDH1A1KDM4EHPGDHSD17B10
Hydrochloric Acid SCHEMBL30797245 0.79 IRAK4 (0.43) IRAK4ALDH1A1KDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2318374-A2 INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE Bayer CropScience AG (DE) 2011-05-11 EP disclosed