Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1835661 | 1.00 | RAB9A (0.45) | RAB9AUSP2HSD11B1ACHEKMT2A | |
| SCHEMBL3239844 | 0.80 | KIF11 (0.44) | ALDH1A1TSHR | |
| SCHEMBL19928063 | 0.79 | ACHE (0.41) | RAB9AUSP2HSD11B1ACHEKMT2A | |
| SCHEMBL11024025 | 0.79 | KMT2A (0.56) | RAB9AUSP2HSD11B1ACHEKMT2A | |
| SCHEMBL8071364 | 0.79 | HSD11B1 (0.52) | RAB9AUSP2HSD11B1ACHEKMT2A | |
| SCHEMBL1835626 | 0.79 | RAB9A (0.48) | RAB9AUSP2HSD11B1ACHEKMT2A | |
| SCHEMBL20143378 | 0.79 | ACHE (0.41) | RAB9AUSP2HSD11B1ACHEKMT2A | |
| SCHEMBL26687541 | 0.77 | KCNN4 (0.48) | RAB9AUSP2HSD11B1ACHEKMT2A | |
| SCHEMBL27650039 | 0.77 | HSD11B1 (0.50) | RAB9AUSP2HSD11B1ACHEKMT2A | |
| SCHEMBL1704452 | 0.75 | KCNN4 (0.41) | RAB9AUSP2HSD11B1ACHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321287-A1 | 4,5-DIHYDRO-OXAZOL-2-YL DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010010014-A1 | 4,5-DIHYDRO-OXAZOL-2-YL DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-01-28 | — | — | WO | disclosed |