Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4798287 | 0.84 | CARM1 (0.53) | TRPA1OPRK1ALDH1A1TSHRADRA2B | |
| SCHEMBL16653971 | 0.81 | OPRK1 (0.45) | DPP7MEN1KMT2AOPRK1OPRM1 | |
| SCHEMBL18002191 | 0.81 | TRPA1 (0.46) | TRPA1MEN1KMT2AOPRK1ALDH1A1 | |
| SCHEMBL13995266 | 0.81 | OPRK1 (0.53) | DPP7OPRK1OPRM1OPRD1ALDH1A1 | |
| SCHEMBL21227439 | 0.79 | HDAC3 (0.47) | DPP7MEN1KMT2AOPRK1OPRM1 | |
| SCHEMBL2310169 | 0.77 | TSHR (0.51) | DPP7MEN1KMT2AOPRK1OPRM1 | |
| SCHEMBL12039805 | 0.77 | OPRK1 (0.53) | MEN1KMT2AOPRK1OPRM1OPRD1 | |
| SCHEMBL9640804 | 0.76 | TSHR (0.54) | MEN1KMT2AOPRK1OPRM1OPRD1 | |
| SCHEMBL8983567 | 0.76 | RIPK1 (0.47) | DPP7OPRK1ALDH1A1TSHRHDAC3 | |
| SCHEMBL11237204 | 0.76 | RIPK1 (0.46) | DPP7MEN1KMT2AOPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2917206-B1 | HETEROARYL SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS KINASE MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2016-12-21 | — | — | EP | disclosed |