SCHEMBL18325596

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL396630	0.79	RIPK1 (0.47)	DPP4PNMTTAAR1SLC6A2RIPK1
	SCHEMBL28710355	0.78	CYP2C19 (0.46)	DPP4PNMTCYP1A2CYP3A4CYP2C9
	SCHEMBL20512217	0.78	HSPA5 (0.48)	MEN1GMNNGABBR2ALDH1A1LMNA
	SCHEMBL17051292	0.78	PDCD1 (0.37)	DPP4MEN1GMNNGABBR2ALDH1A1
	SCHEMBL2958719	0.78	TAAR1 (0.42)	MEN1GMNNGABBR2ALDH1A1LMNA
	SCHEMBL28293880	0.77	TAAR1 (0.52)	DPP4PNMTTAAR1KDM4ESMN1; SMN2
	SCHEMBL6273243	0.73	IDO1 (0.52)	ALDH1A1LMNATAAR1SMN1; SMN2IDO1
	SCHEMBL1744336	0.73	CYP2C19 (0.47)	ALDH1A1LMNACYP1A2CYP3A4CYP2C9
	SCHEMBL20297411	0.73	HPGD (0.45)	MEN1ALDH1A1LMNACYP1A2CYP2C9
	Methylamine SCHEMBL28339099	0.72	PNMT (0.57)	DPP4PNMTTAAR1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.