Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 5/20 | 0.34 |
| ▸ | GABRD | O14764 | 5/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.34 |
| ▸ | GABRE | P78334 | 5/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18325701 | 0.88 | GABRP (0.35) | ALDH1A1LMNAGAATSHRSMN1; SMN2 | |
| SCHEMBL14555805 | 0.81 | LMNA (0.39) | ALDH1A1LMNATSHRNPSR1KDM4E | |
| SCHEMBL15708707 | 0.81 | LMNA (0.60) | ALDH1A1LMNAGAATSHRNPSR1 | |
| SCHEMBL21562972 | 0.81 | GABRP (0.34) | ALDH1A1GAANPSR1GABRPGABRD | |
| SCHEMBL18328262 | 0.73 | LMNA (0.44) | ALDH1A1LMNAGAATSHRNPSR1 | |
| SCHEMBL18209764 | 0.72 | PTPN1 (0.36) | ALDH1A1TSHRGABRPGABRDGABRA1 | |
| SCHEMBL23646937 | 0.72 | MAPK1 (0.38) | ALDH1A1LMNANPSR1SMN1; SMN2GABRP | |
| SCHEMBL18209727 | 0.69 | GABRP (0.41) | ALDH1A1NPSR1GABRPGABRDGABRA1 | |
| SCHEMBL17338781 | 0.68 | PDE4D (0.30) | — | |
| SCHEMBL18325696 | 0.65 | ALDH1A1 (0.44) | ALDH1A1LMNAGAATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160368881-A1 | THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2016-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160368881-A1 | THERAPEUTIC COMPOUNDS | HAVCR2, SARS1, RPL35 | ALDH1A1 429/4885LMNA 3258/4885GAA 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.