Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | UCHL3 | P15374 | 2/20 | 0.38 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15952484 | 0.83 | ESR1 (0.40) | LMNAKDM4E | |
| SCHEMBL10729588 | 0.81 | IDO1 (0.56) | IDO1ALDH1A1L3MBTL1FKBP1ARAB9A | |
| SCHEMBL16021731 | 0.79 | IDO1 (0.47) | IDO1ALDH1A1L3MBTL1FKBP1ARAB9A | |
| SCHEMBL3211356 | 0.77 | GFER (0.59) | ALDH1A1RAB9ANPC1MAOBSMN1; SMN2 | |
| SCHEMBL2222047 | 0.77 | CA2 (0.52) | IDO1ALDH1A1L3MBTL1FKBP1ARAB9A | |
| SCHEMBL24602755 | 0.75 | CYP1A2 (0.52) | IDO1ALDH1A1L3MBTL1RAB9ANPC1 | |
| SCHEMBL10140562 | 0.75 | IDO1 (0.50) | IDO1ALDH1A1L3MBTL1FKBP1ARAB9A | |
| SCHEMBL17722492 | 0.75 | LPL (0.46) | ALDH1A1L3MBTL1RAB9ANPC1HTR1D | |
| SCHEMBL597719 | 0.75 | IDO1 (0.50) | IDO1ALDH1A1L3MBTL1FKBP1AKMT2A | |
| SCHEMBL11745515 | 0.74 | CYP4A11 (0.47) | IDO1ALDH1A1L3MBTL1FKBP1ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160367693-A1 | Selective Arylation of Dichalcogenides in Biomolecules | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160367693-A1 | Selective Arylation of Dichalcogenides in Biomolecules | SCLY, SELENOI, TPO | IDO1 960/4885ALDH1A1 3721/4885L3MBTL1 2233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.