Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.45 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.45 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 7/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 7/20 | 0.39 |
| ▸ | KDM5C | P41229 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | KDM6B | O15054 | 3/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutarate SCHEMBL5874430 | 0.91 | SLC22A6 (0.50) | EGLN1LMNAALKBH5SUCNR1CAMK2A | |
| Adipic Acid SCHEMBL1839163 | 0.91 | GPR84 (0.52) | LMNACAMK2AFOLH1GPR84FFAR1 | |
| Sebacic Acid SCHEMBL5874685 | 0.89 | GPR84 (0.56) | LMNACAMK2AGPR84FFAR1FFAR4 | |
| Malonic Acid SCHEMBL5875306 | 0.87 | LDHA (0.47) | CAMK2AMAPK1TSHR | |
| Glycolic Acid SCHEMBL1830773 | 0.87 | LDHA (0.33) | CAMK2AMAPK1TSHR | |
| Bicarbonate SCHEMBL1832825 | 0.87 | TSHR (0.35) | MAPK1TSHR | |
| Butyric Acid SCHEMBL1834023 | 0.87 | FFAR3 (0.54) | CAMK2AGPR84FFAR1FFAR4OR51E2 | |
| Oxalic Acid SCHEMBL1401648 | 0.84 | TSHR (0.33) | MAPK1OR51E2TSHR | |
| SCHEMBL3317807 | 0.84 | — | — | |
| Valeric Acid SCHEMBL1832380 | 0.83 | AKR1B1 (0.50) | CAMK2AGPR84FFAR1FFAR4OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185330-A1 | Liquids | THE UNIVERSITY OF YORK (GB) | 2007-08-09 | — | — | US | claimed |
| EP-1805131-A2 | IONIC LIQUIDS COMPRISING NITROGEN CONTAINING CATIONS | THE UNIVERSITY OF YORK (GB) | 2007-07-11 | — | — | EP | claimed |
| WO-2005097731-A2 | IONIC LIQUIDS COMPRISING NITROGEN CONTAINING CATIONS | THE UNIVERSITY OF YORK (GB) | 2005-10-20 | — | — | WO | claimed |
| US-20250090437-A1 | COSMETIC COMPOUNDING AGENT, COSMETIC AND PRODUCTION METHOD THEREOF | MIYOSHI YUSHI KK (JP) | 2025-03-20 | — | — | US | disclosed |
| CN-113423470-B | Cosmetic compounding agent, cosmetic, and method for producing same | 三吉油脂株式会社 | 2024-07-09 | — | — | CN | disclosed |
| US-20220096349-A1 | COSMETIC COMPOUNDING AGENT, COSMETIC AND PRODUCTION METHOD THEREOF | MIYOSHI OIL & FAT CO., LTD. (JP) | 2022-03-31 | — | — | US | disclosed |
| EP-3925671-A1 | COSMETIC INGREDIENT, COSMETIC, AND PRODUCTION METHOD FOR COSMETIC | Miyoshi Oil & Fat Co., Ltd. (JP) | 2021-12-22 | — | — | EP | disclosed |
| CN-113423470-A | Cosmetic compounding agent, cosmetic and method for producing same | 三吉油脂株式会社 | 2021-09-21 | — | — | CN | disclosed |
| US-10753038-B2 | Oil solution for carbon fiber precursors and carbon fiber precursor | TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) | 2020-08-25 | — | — | US | disclosed |
| WO-2020166678-A1 | COSMETIC INGREDIENT, COSMETIC, AND PRODUCTION METHOD FOR COSMETIC | ミヨシ油脂株式会社 | 2020-08-20 | — | — | WO | disclosed |
| US-20190234014-A1 | OIL SOLUTION FOR CARBON FIBER PRECURSORS AND CARBON FIBER PRECURSOR | TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) | 2019-08-01 | — | — | US | disclosed |
| CN-101316810-A | Ionic liquids | BIONIQS LTD (GB) | 2008-12-03 | — | — | CN | disclosed |
| US-20080221361-A1 | Ionic Liquids | BIONIQS LIMITED (GB) | 2008-09-11 | — | — | US | disclosed |
| US-20070185330-A1 | Liquids | THE UNIVERSITY OF YORK (GB) | 2007-08-09 | — | — | US | disclosed |
| EP-1805131-A2 | IONIC LIQUIDS COMPRISING NITROGEN CONTAINING CATIONS | THE UNIVERSITY OF YORK (GB) | 2007-07-11 | — | — | EP | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| WO-2005097731-A2 | IONIC LIQUIDS COMPRISING NITROGEN CONTAINING CATIONS | THE UNIVERSITY OF YORK (GB) | 2005-10-20 | — | — | WO | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| EP-0077674-A2 | Viscous compositions containing amidobetaines and salts | UNILEVER PLC (GB) | 1983-04-27 | — | — | EP | disclosed |
| US-4375421-A | COSMETICS, CLEANING COMPOUNDS | LEVER BROTHERS COMPANY (US) | 1983-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190234014-A1 | OIL SOLUTION FOR CARBON FIBER PRECURSORS AND CARBON FIBER PRECURSOR | SGMS2, SGMS1, CNOT7 | EGLN1 777/4885LMNA 57/4885ALKBH5 3592/4885 |
| US-20220096349-A1 | COSMETIC COMPOUNDING AGENT, COSMETIC AND PRODUCTION METHOD THEREOF | H1-0, H1-4, H1-2 | EGLN1 2473/4885LMNA 3310/4885ALKBH5 1345/4885 |
| US-20250090437-A1 | COSMETIC COMPOUNDING AGENT, COSMETIC AND PRODUCTION METHOD THEREOF | CUTA, HAT1, NACA | EGLN1 1872/4885LMNA 3747/4885ALKBH5 783/4885 |
| US-10753038-B2 | Oil solution for carbon fiber precursors and carbon fiber precursor | SGMS2, SGMS1, CNOT7 | EGLN1 777/4885LMNA 57/4885ALKBH5 3592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.