Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.36 |
| ▸ | RORC | P51449 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18332251 | 0.87 | ALOX5 (0.36) | ALOX5NOD1NOD2RORCLMNA | |
| SCHEMBL18331336 | 0.87 | ALOX5 (0.36) | ALOX5NOD1NOD2RORCLMNA | |
| SCHEMBL18331705 | 0.82 | NOD1 (0.47) | ALOX5NOD1NOD2RORCLMNA | |
| SCHEMBL18331337 | 0.80 | ALOX5 (0.38) | ALOX5NOD1NOD2RORCLMNA | |
| SCHEMBL18331797 | 0.79 | ALOX5 (0.35) | ALOX5NOD1NOD2LMNAKDM4E | |
| SCHEMBL18331706 | 0.78 | NOD1 (0.41) | ALOX5NOD1NOD2RORCLMNA | |
| SCHEMBL18332144 | 0.72 | NOD2 (0.56) | NOD1NOD2LMNAKDM4ETSHR | |
| SCHEMBL18332371 | 0.71 | ALOX5 (0.39) | ALOX5NOD1NOD2LMNAKDM4E | |
| SCHEMBL18332148 | 0.71 | NOD2 (0.39) | NOD1NOD2RORCKDM4ETSHR | |
| SCHEMBL18331914 | 0.69 | NOD1 (0.53) | ALOX5NOD1NOD2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016204261-A1 | AMINOPYRAZOLE DERIVATIVES | 中外製薬株式会社 | 2016-12-22 | — | — | WO | disclosed |