Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 4/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18342 | 0.77 | KMO (0.65) | KMOCYP1A2CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL18343 | 0.77 | KMO (0.65) | KMOCYP1A2CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL27964563 | 0.76 | CYP1A2 (0.69) | KMOCYP1A2CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL18032 | 0.75 | KMO (0.67) | KMOALDH1A1CDK2CLK4 | |
| SCHEMBL17610 | 0.74 | HDAC4 (0.38) | KMO | |
| SCHEMBL25428915 | 0.73 | KMO (0.60) | KMOCYP1A2CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL3364843 | 0.73 | KMO (0.60) | KMOCYP1A2CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL935401 | 0.73 | KMO (0.60) | KMOCYP1A2CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL2410452 | 0.70 | LMNA (0.61) | ALDH1A1TDP1LMNA | |
| SCHEMBL18333 | 0.70 | CTSK (0.56) | KMOCYP1A2CYP3A4CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025460-A1 | OXADIAZOLINONE DERIVATIVES AND USE THEREOF IN PEST CONTROL | BAYER CROPSCIENCE AG (DE) | 2012-03-01 | — | — | WO | disclosed |