Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | KDM6B | O15054 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | KDM5C | P41229 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.45 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20028652 | 0.78 | KDM4E (0.46) | PIN1KDM4ELMNACYP1A2POLB | |
| SCHEMBL29852216 | 0.74 | PIN1 (0.53) | PIN1KDM4EKDM6BKDM4AKDM5C | |
| SCHEMBL23294706 | 0.74 | PIN1 (0.53) | PIN1KDM4EKDM6BKDM4AKDM5C | |
| SCHEMBL27901735 | 0.74 | KDM4E (0.48) | KDM4ETGFBR1LMNAL3MBTL1P4HTM | |
| SCHEMBL29799073 | 0.74 | TACR3 (0.44) | PIN1TGFBR1CYP1A2TP53NPC1 | |
| SCHEMBL21296849 | 0.74 | TACR3 (0.44) | PIN1TGFBR1CYP1A2TP53NPC1 | |
| SCHEMBL2791425 | 0.73 | TGFBR1 (0.53) | PIN1KDM4ETGFBR1LMNAL3MBTL1 | |
| SCHEMBL28496295 | 0.73 | TGFBR1 (0.44) | PIN1KDM4EKDM6BKDM4AKDM5C | |
| SCHEMBL3978747 | 0.73 | KDM4E (0.46) | PIN1KDM4ETGFBR1LMNAL3MBTL1 | |
| SCHEMBL7991915 | 0.71 | TGFBR1 (0.57) | PIN1KDM4ETGFBR1CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318472-B1 | ORGANIC LIGHT-EMITTING DIODES FROM HOMOLEPTIC SQUARE PLANAR COMPLEXES | UNIV NORTH TEXAS (US) | 2017-08-23 | — | — | EP | disclosed |
| US-8580397-B2 | Organic light-emitting diodes from homoleptic square planar complexes | UNIVERSITY OF NORTH TEXAS (US) | 2013-11-12 | — | — | US | disclosed |
| US-20110260145-A1 | ORGANIC LIGHT-EMITTING DIODES FROM HOMOLEPTIC SQUARE PLANAR COMPLEXES | UNIVERSITY OF NORTH TEXAS (US) | 2011-10-27 | — | — | US | disclosed |
| US-7960547-B2 | Transition metal complexes with carbene ligands and their application | Cheng, Chien-Hong (TW) | 2011-06-14 | — | — | US | disclosed |
| EP-2318472-A1 | ORGANIC LIGHT-EMITTING DIODES FROM HOMOLEPTIC SQUARE PLANAR COMPLEXES | University Of North Texas (US) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010016990-A1 | ORGANIC LIGHT-EMITTING DIODES FROM HOMOLEPTIC SQUARE PLANAR COMPLEXES | UNIVERSITY OF NORTH TEXAS (US) | 2010-02-11 | — | — | WO | disclosed |
| US-20090149653-A1 | Transition metal complexes with carbene ligands and their application | Cheng, Chien-Hong (TW) | 2009-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149653-A1 | Transition metal complexes with carbene ligands and their application | CCRL2, L1CAM, CHI3L2 | PIN1 944/4885KDM4E 3711/4885KDM6B 3326/4885 |
| US-20110260145-A1 | ORGANIC LIGHT-EMITTING DIODES FROM HOMOLEPTIC SQUARE PLANAR COMPLEXES | PTPRS, PTPRO, PTPRZ1 | PIN1 129/4885KDM4E 3191/4885KDM6B 2910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.