Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16879344 | 0.91 | TDP1 (0.49) | TDP1L3MBTL1PDK2HSD17B3KDM1A | |
| SCHEMBL16878998 | 0.88 | TDP1 (0.50) | TDP1L3MBTL1PDK2HSD17B3KDM1A | |
| SCHEMBL14831134 | 0.86 | PDK2 (0.49) | TDP1L3MBTL1PDK2ALDH1A1MAPK1 | |
| SCHEMBL23989351 | 0.86 | PDK2 (0.49) | TDP1L3MBTL1PDK2ALDH1A1MAPK1 | |
| SCHEMBL18347143 | 0.85 | TDP1 (0.45) | TDP1L3MBTL1PDK2HSD17B3KDM1A | |
| SCHEMBL16656146 | 0.84 | ALDH1A1 (0.42) | PDK2ALDH1A1MAPK1PTPRCMAOA | |
| SCHEMBL17533935 | 0.81 | PDK2 (0.46) | TDP1L3MBTL1PDK2ALDH1A1PTPRC | |
| SCHEMBL14208142 | 0.80 | PDK2 (0.50) | TDP1L3MBTL1PDK2ALDH1A1MAPK1 | |
| SCHEMBL15316154 | 0.79 | BACE1 (0.35) | TDP1L3MBTL1PDK2HSD17B3KDM1A | |
| SCHEMBL19164108 | 0.79 | PDK2 (0.49) | TDP1L3MBTL1PDK2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160380203-A1 | DIBENZOSUBERANE-BASED ELECTRON-TRANSPORT MATERIALS | JENEKHE SAMSON A (US) | 2016-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160380203-A1 | DIBENZOSUBERANE-BASED ELECTRON-TRANSPORT MATERIALS | SLC6A12, SLC19A2, ABCB7 | TDP1 1717/4885L3MBTL1 3058/4885PDK2 813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.