SCHEMBL183540

SCHEMBL183540

CN1C[C@H](C(N)=O)C=C2c3cccc4[nH]cc(c34)C[C@H]21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.80
MEN1 O00255 3/20 0.80
KMT2A Q03164 3/20 0.80
MAPT P10636 2/20 0.80
RECQL P46063 2/20 0.80
USP2 O75604 1/20 0.80
PLEC Q15149 1/20 0.80
DRD2 P14416 5/20 0.74
DRD3 P35462 5/20 0.74
HTR2B P41595 5/20 0.74
HTR6 P50406 5/20 0.74
HTR2A P28223 5/20 0.74
HTR1A P08908 4/20 0.74
DRD4 P21917 4/20 0.74
DRD5 P21918 4/20 0.74
HTR1D P28221 4/20 0.74
HTR1E P28566 4/20 0.74
HTR7 P34969 4/20 0.74
HRH1 P35367 4/20 0.74
HTR5A P47898 4/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10400706 1.00 KDM4E (0.80) KDM4EMEN1KMT2AMAPTRECQL
SCHEMBL10400862 1.00 KDM4E (0.80) KDM4EMEN1KMT2AMAPTRECQL
SCHEMBL26265228 1.00 KDM4E (0.80) KDM4EMEN1KMT2AMAPTRECQL
SCHEMBL31079495 1.00 KDM4E (0.80) KDM4EMEN1KMT2AMAPTRECQL
SCHEMBL30797592 1.00 KDM4E (0.80) KDM4EMEN1KMT2AMAPTRECQL
Carbamic Acid SCHEMBL31692730 0.98 KDM4E (0.77) KDM4EMEN1KMT2AMAPTRECQL
Methylsulfanylmethane SCHEMBL27454519 0.97 KDM4E (0.76) KDM4EMEN1KMT2AMAPTRECQL
Cadaverine Tartrate SCHEMBL28748097 0.93 MEN1 (0.71) KDM4EMEN1KMT2AMAPTRECQL
Cadaverine Tartrate SCHEMBL31561354 0.93 MEN1 (0.71) KDM4EMEN1KMT2AMAPTRECQL
Acetamide SCHEMBL29094036 0.92 KDM4E (0.74) KDM4EMEN1KMT2AMAPTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12605345-B2 Transdermal drug delivery system BioPhysics Pharma, Inc. (US) 2026-04-21 US claimed
EP-4704826-A1 COMPOSITIONS AND METHODS FOR TREATING POST-TRAUMATIC STRESS DISORDER Yale University (US) 2026-03-11 EP claimed
WO-2026043908-A1 COMPOSITIONS AND METHODS TO IMPROVE SEQUESTRATION OF MYCOTOXINS AND THEIR USE IN DETOXIFICATION OF ANIMAL FEED AND ANIMAL PRODUCTION SYSTEMS ALLTECH, INC. (US) 2026-02-26 WO claimed
EP-4674894-A2 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES Hemoteq AG (DE) 2026-01-07 EP claimed
US-12514883-B2 Compositions and methods for modulating lipid and steroid metabolism THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-01-06 US claimed
EP-4663688-A2 CROSSLINKERS Hemoteq AG (DE) 2025-12-17 EP claimed
US-20250375420-A1 COMPOSITIONS AND USES OF PSILOCYBIN AND PSILOCIN ZYLORION HEALTH INC (CA) 2025-12-11 US claimed
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES INC (US) 2025-11-27 US claimed
EP-4633638-A1 TREATMENT OF PSYCHOLOGICAL FACTORS AFFECTING OTHER MEDICAL CONDITIONS (PFAOMC) Luminous Mind Inc. (US) 2025-10-22 EP claimed
EP-4618980-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES Freedom Biosciences, Inc. (US) 2025-09-24 EP claimed
US-20040077039-A1 Modulation of secondary metabolite production by zinc binuclear... DSM IP ASSETS B.V. (NL) 2004-04-22 US claimed
EP-1409530-A2 MODULATION OF SECONDARY METABOLITE PRODUCTION BY ZINC BINUCLEAR CLUSTER PROTEINS Microbia, Inc. (US) 2004-04-21 EP claimed
US-20040052731-A1 Abuse-deterrent pharmaceutical compositions of opiods and other drugs COLLEGIUM PHARMACEUTICALS, INC. 2004-03-18 US claimed
WO-2004004693-A1 ABUSE-DETERRENT PHARMACEUTICAL COMPOSITIONS OF OPIODS AND OTHER DRUGS COLLGEGIUM PHARMACEUTICAL (US) 2004-01-15 WO claimed
WO-2002024865-A2 MODULATION OF SECONDARY METABOLITE PRODUCTION BY ZINC BINUCLEAR CLUSTER PROTEINS MICROBIA, INC. (US) 2002-03-28 WO claimed
CN-1067956-A Make the method and apparatus of nitrogen for ultra-high purity BOC GROUP INC (US) 1993-01-13 CN claimed
EP-0205068-B1 LYSERGIC-ACID AMIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM ARZNEIMITTELWERK DRESDEN GmbH (DE) 1992-01-02 EP claimed
EP-0095092-B1 PROCESS FOR THE PREPARATION OF LYSERGIC ACID ESTERS SCHERING AKTIENGESELLSCHAFT (DE) 1986-12-30 EP claimed
US-4524208-A Process for the preparation of lysergic acid esters SCHERING AKTIENGESELLSCHAFT (DE) 1985-06-18 US claimed
EP-0095092-A2 Process for the preparation of lysergic acid esters SCHERING AKTIENGESELLSCHAFT (DE) 1983-11-30 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES PDE9A, PDE3A, PDE2A KDM4E 1355/4885MEN1 2211/4885KMT2A 1149/4885
US-20250375420-A1 COMPOSITIONS AND USES OF PSILOCYBIN AND PSILOCIN BDNF, NGF, PYGB KDM4E 4566/4885MEN1 3812/4885KMT2A 4247/4885
US-12605345-B2 Transdermal drug delivery system FABP2, VEGFA, CUTA KDM4E 1352/4885MEN1 922/4885KMT2A 2706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.