Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5898485 | 0.86 | HCAR2 (0.74) | HCAR2LMNAALDH1A1CTSLL3MBTL1 | |
| SCHEMBL5897900 | 0.86 | HCAR2 (0.74) | HCAR2LMNAALDH1A1CTSLL3MBTL1 | |
| SCHEMBL5897892 | 0.86 | HCAR2 (0.74) | HCAR2LMNAALDH1A1CTSLL3MBTL1 | |
| SCHEMBL16092878 | 0.86 | LMNA (0.65) | HCAR2LMNASMN1; SMN2HTTTGM2 | |
| Ammonia Solution, Strong SCHEMBL27556861 | 0.85 | HCAR2 (0.72) | HCAR2LMNAALDH1A1CTSLL3MBTL1 | |
| SCHEMBL18354925 | 0.84 | HTT (0.59) | HCAR2LMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL8551054 | 0.83 | SMN1; SMN2 (0.52) | HCAR2LMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL18352682 | 0.83 | TGM2 (0.58) | HCAR2LMNASMN1; SMN2HTTTGM2 | |
| SCHEMBL18353212 | 0.82 | TGM2 (0.60) | HCAR2LMNASMN1; SMN2HTTTGM2 | |
| SCHEMBL18353024 | 0.82 | TGM2 (0.60) | HCAR2LMNASMN1; SMN2HTTTGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170001953-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | Nguyen, Mark Quang (US) | 2017-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170001953-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | FH, FPGS, APC | HCAR2 290/4885LMNA 4358/4885SMN1; SMN2 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.