Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL761110 | 0.80 | CES2 (0.44) | SMN1; SMN2KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL242690 | 0.80 | CES2 (0.41) | SMN1; SMN2ALDH1A1NPC1RAB9AGAA | |
| SCHEMBL1834219 | 0.75 | KMT2A (0.45) | SMN1; SMN2KDM4EKMT2AALDH1A1RAB9A | |
| SCHEMBL27455343 | 0.70 | MGAM (0.47) | ALPLSMN1; SMN2KDM4EKMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL1835867 | 0.70 | CNR2 (0.40) | CNR2FAAHALPLSMN1; SMN2KDM4E | |
| SCHEMBL10492099 | 0.70 | HDAC1 (0.44) | SMN1; SMN2KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL10584041 | 0.70 | LTA4H (0.42) | CNR2SMN1; SMN2KDM4EKMT2AHPGD | |
| SCHEMBL107377 | 0.69 | CES1 (0.42) | FAAH | |
| SCHEMBL3167320 | 0.68 | RAB9A (0.41) | KDM4EKMT2AALDH1A1HPGDLMNA | |
| SCHEMBL7584607 | 0.68 | LTA4H (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466313-B2 | Fluoridation of iodonium salts | GE HEALTHCARE LIMITED (GB) | 2013-06-18 | — | — | US | disclosed |
| US-20110144344-A1 | FLUORIDATION OF IODONIUM SALTS | GE HEALTHCARE LIMITED (GB) | 2011-06-16 | — | — | US | disclosed |
| EP-2321237-A2 | IMPROVED FLUORIDATION OF IODONIUM SALTS | GE Healthcare UK Limited (GB) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010018218-A2 | IMPROVED FLUORIDATION OF IODONIUM SALTS | GE HEALTHCARE LIMITED (GB) | 2010-02-18 | — | — | WO | disclosed |
| WO-2007141529-A1 | FLUORIDATION METHOD | GE HEALTHCARE LIMITED (GB) | 2007-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144344-A1 | FLUORIDATION OF IODONIUM SALTS | ARF5, IPO5, SAMHD1 | CNR2 4473/4885FAAH 1372/4885ALPL 1625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.