Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14493665 | 0.89 | L3MBTL1 (0.58) | L3MBTL1PKMALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL164232 | 0.89 | L3MBTL1 (0.58) | L3MBTL1PKMALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13589980 | 0.89 | L3MBTL1 (0.58) | L3MBTL1PKMALDH1A1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL1061966 | 0.87 | L3MBTL1 (0.61) | L3MBTL1PKMALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5486305 | 0.87 | L3MBTL1 (0.56) | L3MBTL1PKMALDH1A1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL4712251 | 0.87 | L3MBTL1 (0.61) | L3MBTL1PKMALDH1A1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL4712253 | 0.87 | L3MBTL1 (0.61) | L3MBTL1PKMALDH1A1SMN1; SMN2LMNA | |
| Methacrylic Acid SCHEMBL29283555 | 0.84 | ALDH1A1 (0.53) | L3MBTL1PKMALDH1A1SMN1; SMN2LMNA | |
| Acrylic Acid SCHEMBL29281850 | 0.82 | PKM (0.49) | L3MBTL1PKMALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5562998 | 0.81 | L3MBTL1 (0.51) | L3MBTL1PKMALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170008915-A1 | ACID, SOLVENT, AND THERMAL RESISTANT METAL-ORGANIC FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170008915-A1 | ACID, SOLVENT, AND THERMAL RESISTANT METAL-ORGANIC FRAMEWORKS | HAO2, ASF1A, FTO | L3MBTL1 2166/4885PKM 1091/4885ALDH1A1 639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.