SCHEMBL18364697

SCHEMBL18364697

CCCCCCCCC(CCCCCCCC)COc1ccc(C(=O)CC(=O)OCC)cc1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.47
PLA2G4B P0C869 2/20 0.46
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44
THRA P10827 3/20 0.43
THRB P10828 3/20 0.43
HRH2 P25021 2/20 0.43
HRH1 P35367 2/20 0.43
NPC1 O15118 1/20 0.43
MAPT P10636 1/20 0.42
MMP1 P03956 1/20 0.42
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
RARB P10826 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9505212 0.84 TP53 (0.61) L3MBTL1PLA2G4BTP53TSHRTHRA
SCHEMBL8403564 0.84 TP53 (0.61) L3MBTL1PLA2G4BTP53TSHRTHRA
SCHEMBL1436716 0.83 TP53 (0.59) L3MBTL1PLA2G4BTP53TSHRTHRA
SCHEMBL9172925 0.83 MMP1 (0.58) L3MBTL1PLA2G4BTP53TSHRTHRA
SCHEMBL31439624 0.82 TP53 (0.57) L3MBTL1PLA2G4BTP53TSHRTHRA
SCHEMBL3842241 0.82 PLA2G4B (0.55) PLA2G4BTP53TSHRTHRATHRB
SCHEMBL18364696 0.81 MEN1 (0.43) L3MBTL1PLA2G4BTP53TSHRMAPT
SCHEMBL10784668 0.80 PLA2G4B (0.68) PLA2G4BTP53TSHRMAPK1RARB
SCHEMBL10785284 0.79 PLA2G4B (0.67) PLA2G4BTP53TSHRMAPK1RARB
SCHEMBL11830013 0.78 NPC1 (0.62) L3MBTL1PLA2G4BNPC1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170012072-A1 INFRARED SENSOR, NEAR-INFRARED ABSORBING COMPOSITION, CURED FILM, NEAR-INFRARED ABSORBING FILTER, IMAGE SENSOR, CAMERA MODULE, AND COMPOUND FUJIFILM CORPORATION (JP) 2017-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170012072-A1 INFRARED SENSOR, NEAR-INFRARED ABSORBING COMPOSITION, CURED FILM, NEAR-INFRARED ABSORBING FILTER, IMAGE SENSOR, CAMERA MODULE, AND COMPOUND TRPA1, CRY1, ASIC1 L3MBTL1 4547/4885PLA2G4B 4617/4885TP53 2378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.