SCHEMBL18375385

SCHEMBL18375385

N#Cc1ccc(-c2cc3cc(-c4ccc(C#N)cc4)c(-c4ccc(C#N)cc4)cc3cc2-c2ccc(C#N)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 1/20 0.50
KIF11 P52732 3/20 0.45
CYP11B2 P19099 4/20 0.44
CA12 O43570 2/20 0.44
CA2 P00918 2/20 0.44
CA9 Q16790 2/20 0.44
ALDH1A1 P00352 1/20 0.44
CYP2A6 P11509 1/20 0.44
CA3 P07451 1/20 0.44
CA6 P23280 1/20 0.44
CA14 Q9ULX7 1/20 0.44
PGR P06401 3/20 0.44
PTGS1 P23219 1/20 0.43
CA1 P00915 1/20 0.42
TSHR P16473 1/20 0.42
SLC22A12 Q96S37 1/20 0.41
GAA P10253 1/20 0.41
NOTUM Q6P988 1/20 0.41
RIPK1 Q13546 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19579263 0.81 KIF11 (0.52) MMP3KIF11CYP11B2CA12CA2
SCHEMBL17239819 0.81 MMP3 (0.58) MMP3KIF11CYP11B2CA12CA2
SCHEMBL30494512 0.81 MMP3 (0.46) MMP3KIF11CYP11B2CA12CA2
SCHEMBL30153654 0.81 MMP3 (0.46) MMP3KIF11CYP11B2CA12CA2
SCHEMBL23841434 0.78 ABCG2 (0.51) CYP11B2ALDH1A1TSHRSLC22A12
SCHEMBL13063633 0.78 MMP3 (0.74) MMP3KIF11CYP11B2CA12CA2
SCHEMBL396846 0.78 MMP3 (0.74) MMP3KIF11CYP11B2CA12CA2
Water SCHEMBL11055485 0.78 MMP3 (0.74) MMP3KIF11CYP11B2CA12CA2
SCHEMBL26246 0.78 MMP3 (0.74) MMP3KIF11CYP11B2CA12CA2
SCHEMBL19939322 0.78 ABCG2 (0.55) CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11522137-B2 Organic light emitting element, display device, image information processing device, lighting device, image forming device, exposure device, and organic photoelectric conversion element CANON KABUSHIKI KAISHA (JP) 2022-12-06 US disclosed
US-10403827-B2 2,2′-bibenzo[D]imidazolidene compound having condensed rings at the 1-, 1′-, 3- and 3′-positions, and organic light-emitting element, display device, image information processing apparatus, lighting device, image forming apparatus and exposure unit, each containing the same CANON KABUSHIKI KAISHA (JP) 2019-09-03 US disclosed
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same CANON KABUSHIKI KAISHA (JP) 2019-01-29 US disclosed
US-9882148-B2 Organic compound, field element, organic light-emitting element, display apparatus, image information-processing apparatus, lighting apparatus, image-forming apparatus, and exposure apparatus CANON KABUSHIKI KAISHA (JP) 2018-01-30 US disclosed
US-20170263870-A1 2,2'-BIBENZO[D]IMIDAZOLIDENE COMPOUND HAVING CONDENSED RINGS AT THE 1-, 1'-, 3- AND 3'-POSITIONS, AND ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, IMAGE INFORMATION PROCESSING APPARATUS, LIGHTING DEVICE, IMAGE FORMING APPARATUS AND EXPOSURE UNIT, EACH CONTAINING THE SAME CANON KABUSHIKI KAISHA (JP) 2017-09-14 US disclosed
US-20170155059-A1 ORGANIC COMPOUND, FIELD ELEMENT, ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY APPARATUS, IMAGE INFORMATION-PROCESSING APPARATUS, LIGHTING APPARATUS, IMAGE-FORMING APPARATUS, AND EXPOSURE APPARATUS CANON KABUSHIKI KAISHA (JP) 2017-06-01 US disclosed
US-20170012215-A1 ORGANIC LIGHT EMITTING ELEMENT, DISPLAY DEVICE, IMAGE INFORMATION PROCESSING DEVICE, LIGHTING DEVICE, IMAGE FORMING DEVICE, EXPOSURE DEVICE, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT CANON KABUSHIKI KAISHA (JP) 2017-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170155059-A1 ORGANIC COMPOUND, FIELD ELEMENT, ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY APPARATUS, IMAGE INFORMATION-PROCESSING APPARATUS, LIGHTING APPARATUS, IMAGE-FORMING APPARATUS, AND EXPOSURE APPARATUS SCO2, OGFOD1, OXER1 MMP3 4471/4885KIF11 4233/4885CYP11B2 543/4885
US-20170263870-A1 2,2'-BIBENZO[D]IMIDAZOLIDENE COMPOUND HAVING CONDENSED RINGS AT THE 1-, 1'-, 3- AND 3'-POSITIONS, AND ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, IMAGE INFORMATION PROCESSING APPARATUS, LIGHTING DEVICE, IMAGE FORMING APPARATUS AND EXPOSURE UNIT, EACH CONTAINING THE SAME GRK1, BRD1, BRD8 MMP3 4666/4885KIF11 3038/4885CYP11B2 1202/4885
US-11522137-B2 Organic light emitting element, display device, image information processing device, lighting device, image forming device, exposure device, and organic photoelectric conversion element AHR, CYP1A1, CYP1B1 MMP3 4579/4885KIF11 4511/4885CYP11B2 516/4885
US-20170012215-A1 ORGANIC LIGHT EMITTING ELEMENT, DISPLAY DEVICE, IMAGE INFORMATION PROCESSING DEVICE, LIGHTING DEVICE, IMAGE FORMING DEVICE, EXPOSURE DEVICE, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT AHR, CYP1A1, CYP1B1 MMP3 4579/4885KIF11 4511/4885CYP11B2 516/4885
US-10403827-B2 2,2′-bibenzo[D]imidazolidene compound having condensed rings at the 1-, 1′-, 3- and 3′-positions, and organic light-emitting element, display device, image information processing apparatus, lighting device, image forming apparatus and exposure unit, each containing the same GRK1, BRD1, BRD8 MMP3 4662/4885KIF11 3040/4885CYP11B2 1289/4885
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same BRD1, DRD1, NR2E3 MMP3 4616/4885KIF11 3941/4885CYP11B2 1608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.