SCHEMBL183857

SCHEMBL183857

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nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.52
LMNA P02545 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
TDP1 Q9NUW8 2/20 0.48
USP2 O75604 1/20 0.43
SLCO1B1 Q9Y6L6 1/20 0.43
KDM4E B2RXH2 2/20 0.41
OR51E2 Q9H255 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP2C9 P11712 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL539547 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL3394266 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL2621334 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL3390883 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL1521506 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL30854359 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL30854351 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL1671746 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL342905 0.92 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL9961490 0.92 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 313 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120060384-A Biological method for preparing 1, 2-propanediol 天津大学 2025-05-30 CN claimed
CN-120060228-A Polypeptides for biosynthesis of 1, 2-propanediol and uses thereof 天津大学 2025-05-30 CN claimed
CN-118961909-A Burley tobacco baking uniformity evaluation method based on multi-index feature marker detection 上海烟草集团有限责任公司 2024-11-15 CN claimed
CN-117903386-A Method for realizing liquid phase polymerization of high-concentration polyhydroxy aldehyde or (and) polyhydroxy ketone through liquid thereof under high-temperature condition 厦门碳控科技投资有限公司 2024-04-19 CN claimed
US-20240041944-A1 OPTIMIZED INDIVIDUALIZED PREBIOTIC COMPOSITIONS ISOTHRIVE LLC 2024-02-08 US claimed
CN-116953112-A Analysis method for simultaneously determining sugar, organic acid, amino acid and Maillard reaction product in tobacco flavor 浙江中烟工业有限责任公司 2023-10-27 CN claimed
CN-115197780-A Method for preparing heterocyclic compound from sugar-amino acid condensate and application of heterocyclic compound 河南中烟工业有限责任公司 2022-10-18 CN claimed
CN-111638363-B 3-deoxyfructose rapid quantitative fluorescence detection device and preparation method thereof 吉林省格瑞斯特生物技术有限公司 2022-02-18 CN claimed
US-20210386683-A1 COMPOSITIONS AND METHODS RELATING TO RESVERATROL WILMORE LABS, LLC 2021-12-16 US claimed
CN-111638363-A 3-deoxyfructose rapid quantitative fluorescence detection device and preparation method thereof 吉林省格瑞斯特生物技术有限公司 2020-09-08 CN claimed
CN-1148185-C Inhibitor for generation of 3-deoxyglucurone �ձ���ҩ��ʽ���� 2004-05-05 CN claimed
WO-1999053930-A1 SYNTHETIC GLYCOAMINES AND METHODS FOR THEIR USE, ALONE OR IN COMBINATION WITH OTHER THERAPIES, THAT AFFECT CELL ADHESION, INHIBIT CANCER CELL GROWTH AND METASTASIS, AND INDUCE APOPTOSIS GLINSKII GUENNADI V (US) 1999-10-28 WO claimed
EP-0944639-A1 SYNTHETIC GLYCOAMINES, METHODS FOR THEIR USE THAT AFFECT CELL Glinskii, Guennadi, V. (US) 1999-09-29 EP claimed
US-5864024-A BRINGING CELLS INTO CONTACT WITH A COMPOUND COMPRISING A POLYPEPTIDE HAVING AN AMINO ACID LINKED TO A CARBOHYDRATE TO FORM A COMPOUND CHOSEN FROM THE GROUP CONSISTING OF SCHIFF BASES, N-GLYCOSIDES, ESTERS, AMADORI PRODUCTS NIH - DEITR 1999-01-26 US claimed
EP-0731704-A4 SYNTHETIC GLYCOAMINES THAT PROMOTE OR INHIBIT CELL ADHESION METASTAT INC (US) 1998-12-30 EP claimed
WO-1998023625-A9 SYNTHETIC GLYCOAMINES, METHODS FOR THEIR USE THAT AFFECT CELL 1998-09-17 WO claimed
WO-1998023625-A1 SYNTHETIC GLYCOAMINES, METHODS FOR THEIR USE THAT AFFECT CELL GLINSKII GUENNADI V (US) 1998-06-04 WO claimed
US-5629412-A POLYPEPTIDE AND CARBOHYDRATE GLINSKII GUENNADI V (US) 1997-05-13 US claimed
EP-0731704-A1 SYNTHETIC GLYCOAMINES THAT PROMOTE OR INHIBIT CELL ADHESION METASTAT, INC. (US) 1996-09-18 EP claimed
WO-1996001639-A1 SYNTHETIC GLYCOAMINES THAT PROMOTE OR INHIBIT CELL ADHESION METASTAT, INC. (US) 1996-01-25 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240041944-A1 OPTIMIZED INDIVIDUALIZED PREBIOTIC COMPOSITIONS DDOST, STT3A, SI PDE4A 2526/4885LMNA 689/4885L3MBTL1 1652/4885
US-20210386683-A1 COMPOSITIONS AND METHODS RELATING TO RESVERATROL ATP6V1B2, PSEN1, APP PDE4A 3528/4885LMNA 1214/4885L3MBTL1 4168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.