SCHEMBL539547

SCHEMBL539547

CC(=O)[C@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.52
LMNA P02545 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
TDP1 Q9NUW8 2/20 0.48
USP2 O75604 1/20 0.43
SLCO1B1 Q9Y6L6 1/20 0.43
KDM4E B2RXH2 2/20 0.41
OR51E2 Q9H255 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP2C9 P11712 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3394266 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL2621334 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL3390883 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL183857 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL1521506 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL30854359 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL30854351 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL1671746 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL342905 0.92 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL9961490 0.92 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 544 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117903386-A Method for realizing liquid phase polymerization of high-concentration polyhydroxy aldehyde or (and) polyhydroxy ketone through liquid thereof under high-temperature condition 厦门碳控科技投资有限公司 2024-04-19 CN claimed
US-20240041944-A1 OPTIMIZED INDIVIDUALIZED PREBIOTIC COMPOSITIONS ISOTHRIVE LLC 2024-02-08 US claimed
EP-4314332-A2 METHODS FOR IDENTIFICATION AND RATIO DETERMINATION OF RNA SPECIES IN MULTIVALENT RNA COMPOSITIONS ModernaTX, Inc. (US) 2024-02-07 EP claimed
EP-3166615-B1 CHELATED PHOSPHOROTIOTATED NUCLEIC ACID POLYMERS FOR USE IN COMBINATION WITH A HBV POLYMERASE INHIBITOR FOR THE TREATMENT OF HEPATITIS B AND HEPATITIS D VIRUS INFECTIONS REPLICOR INC (CA) 2023-08-09 EP claimed
EP-3047023-B1 COMPOSITIONS AND METHODS FOR INHIBITING JC VIRUS (JCV) US HEALTH (US) 2019-09-04 EP claimed
CN-110121562-A Method of producing a composite material 牛津纳米孔技术公司 2019-08-13 CN claimed
CN-109206464-A A kind of adenosine diphosphate core saccharide compound and preparation method thereof and bioactivity 北京大学 2019-01-15 CN claimed
CN-108866058-A It targets the siRNA of KRAS and its is preparing the application in treatment of pancreatic cancer drug 苏州吉玛基因股份有限公司 2018-11-23 CN claimed
US-10036020-B2 Compositions and methods for inhibiting JC virus (JCV) THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) 2018-07-31 US claimed
US-9994856-B2 Method for increasing the activity of a cystic fibrosis transmembrane conductance regulator protein PROQR THERAPEUTICS II B.V. (NL) 2018-06-12 US claimed
US-6423867-B1 FROM TRI-O-ACETYL-D-ERYTHRO-4-PENTULOSONIC ACID ESTERS BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY 2002-07-23 US claimed
US-20020026071-A1 Process and intermediate compounds for the preparation of pyrrolidines BOARD OF TRUSTEES, OPERATING MICHIGAN STATE UNIVERSITY 2002-02-28 US claimed
US-20020026073-A1 Process and intermediate compounds for the preparation of pyrrolidines BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY 2002-02-28 US claimed
US-20020026072-A1 Process and intermediate compounds for the preparation of pyrrolidines BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) 2002-02-28 US claimed
US-20020026074-A1 Process and intermediate compounds for the preparation of pyrrolidines BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERS 2002-02-28 US claimed
US-20020019542-A1 Process and intermediate compounds for the preparation of pyrrolidines MICHIGAN STATE UNIVERSITY BOARD OF TRUSTEES OPERATING 2002-02-14 US claimed
US-20020019561-A1 Process and intermediate compounds for the preparation of pyrrolidines BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY 2002-02-14 US claimed
WO-2002010130-A1 PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES MICHIGAN STATE UNIVERSITY (US) 2002-02-07 WO claimed
EP-0672171-A1 FORMATION OF TRIPLE HELIX COMPLEXES OF DOUBLE STRANDED DNA USING NUCLEOSIDE OLIGOMERS WHICH COMPRISE PURINE BASE ANALOGS THE JOHNS HOPKINS UNIVERSITY (US) 1995-09-20 EP claimed
WO-1993005180-A1 FORMATION OF TRIPLE HELIX COMPLEXES OF DOUBLE STRANDED DNA USING NUCLEOSIDE OLIGOMERS WHICH COMPRISE PURINE BASE ANALOGS THE JOHNS HOPKINS UNIVERSITY (US) 1993-03-18 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020026073-A1 Process and intermediate compounds for the preparation of pyrrolidines UMPS, DUT, DPYD PDE4A 935/4885LMNA 2986/4885L3MBTL1 4143/4885
US-20020026071-A1 Process and intermediate compounds for the preparation of pyrrolidines UMPS, DUT, DPYD PDE4A 935/4885LMNA 2986/4885L3MBTL1 4143/4885
US-20020019542-A1 Process and intermediate compounds for the preparation of pyrrolidines UMPS, DUT, DPYD PDE4A 935/4885LMNA 2986/4885L3MBTL1 4143/4885
US-20020026074-A1 Process and intermediate compounds for the preparation of pyrrolidines UMPS, DUT, DPYD PDE4A 935/4885LMNA 2986/4885L3MBTL1 4143/4885
US-20020026072-A1 Process and intermediate compounds for the preparation of pyrrolidines UMPS, DUT, DPYD PDE4A 935/4885LMNA 2986/4885L3MBTL1 4143/4885
US-20020019561-A1 Process and intermediate compounds for the preparation of pyrrolidines UMPS, DUT, DPYD PDE4A 935/4885LMNA 2986/4885L3MBTL1 4143/4885
US-20240041944-A1 OPTIMIZED INDIVIDUALIZED PREBIOTIC COMPOSITIONS DDOST, STT3A, SI PDE4A 2526/4885LMNA 689/4885L3MBTL1 1652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.