SCHEMBL1671746

SCHEMBL1671746

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nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.52
LMNA P02545 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
TDP1 Q9NUW8 2/20 0.48
USP2 O75604 1/20 0.43
SLCO1B1 Q9Y6L6 1/20 0.43
KDM4E B2RXH2 2/20 0.41
OR51E2 Q9H255 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP2C9 P11712 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL539547 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL3394266 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL2621334 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL3390883 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL183857 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL1521506 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL30854359 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL30854351 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL342905 0.92 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL9961490 0.92 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2096164-B1 MICROORGANISM CAPABLE OF PRODUCING DEOXY POLYOL DEHYDROGENASE AND UTILIZATION OF THE SAME UNIV KAGAWA NAT UNIV CORP (JP) 2016-05-11 EP claimed
US-8530222-B2 Microorganism with ability to produce deoxy polyol dehydrogenase and use thereof NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY (JP) 2013-09-10 US claimed
US-20100167350-A1 MICROORGANISM WITH ABILITY TO PRODUCE DEOXY POLYOL DEHYDROGENASE AND USE THEREOF NAT'L UNIVERSITY CORPORATION KAGAWA UNIVERSITY (JP) 2010-07-01 US claimed
EP-2096164-A1 MICROORGANISM CAPABLE OF PRODUCING DEOXY POLYOL DEHYDROGENASE AND UTILIZATION OF THE SAME National University Corporation Kagawa University (JP) 2009-09-02 EP claimed
US-4340671-A E. coli sensitivity broth MCDONNELL DOUGLAS CORPORATION (US) 1982-07-20 US claimed
CN-118895219-B Endophytic bacterium for inducing ginseng to accumulate saponins and application thereof 中国中医科学院中药研究所 2025-03-25 CN disclosed
CN-119162273-A Boron-containing composition for preparing lactulose, preparation method and application thereof 中国科学院天津工业生物技术研究所 2024-12-20 CN disclosed
CN-119162267-A Boron-containing composition, preparation method and application thereof 中国科学院天津工业生物技术研究所 2024-12-20 CN disclosed
CN-118895219-A Endophytic bacterium for inducing ginseng to accumulate saponins and application thereof 中国中医科学院中药研究所 2024-11-05 CN disclosed
CN-115948258-B Rhodotorula palustris XY11 strain for producing PEFA and application thereof 中国海洋大学 2024-04-02 CN disclosed
CN-115948258-A Rhodotorula palustris XY11 strain for producing PEFA and application thereof 中国海洋大学 2023-04-11 CN disclosed
EP-2096164-B1 MICROORGANISM CAPABLE OF PRODUCING DEOXY POLYOL DEHYDROGENASE AND UTILIZATION OF THE SAME UNIV KAGAWA NAT UNIV CORP (JP) 2016-05-11 EP disclosed
EP-2161332-A1 DEOXYKETOHEXOSE ISOMERASE AND METHOD FOR PRODUCING DEOXYKETOHEXOSE AND DERIVATIVE THEREOF USING THE SAME National University Corporation Kagawa University (JP) 2010-03-10 EP disclosed
EP-2096164-A1 MICROORGANISM CAPABLE OF PRODUCING DEOXY POLYOL DEHYDROGENASE AND UTILIZATION OF THE SAME National University Corporation Kagawa University (JP) 2009-09-02 EP disclosed
EP-2096164-A1 MICROORGANISM CAPABLE OF PRODUCING DEOXY POLYOL DEHYDROGENASE AND UTILIZATION OF THE SAME National University Corporation Kagawa University (JP) 2009-09-02 EP disclosed
WO-2008062570-A1 MICROORGANISM CAPABLE OF PRODUCING DEOXY POLYOL DEHYDROGENASE AND UTILIZATION OF THE SAME NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY (JP) 2008-05-29 WO disclosed
US-20060234363-A1 Synthesis of 1,2,4-butanetriol enantiomers from carbohydrates BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY 2006-10-19 US disclosed
WO-2005068642-A2 BACTERIAL SYNTHESIS OF 1,2,4-BUTANETRIOL ENANTIOMERS BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) 2005-07-28 WO disclosed
US-20030144501-A1 Conformationally constrained L-nucleosides ISIS PHARMACEUTICALS, INC. 2003-07-31 US disclosed
US-6525191-B1 A nucleobase is glycosidically linked to a sugar or sugar-like ring IONIS PHARMACEUTICALS, INC. 2003-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030144501-A1 Conformationally constrained L-nucleosides NSUN2, DCK, DCTD PDE4A 2495/4885LMNA 599/4885L3MBTL1 116/4885
US-20100167350-A1 MICROORGANISM WITH ABILITY TO PRODUCE DEOXY POLYOL DEHYDROGENASE AND USE THEREOF DCXR, SI, SORD PDE4A 3035/4885LMNA 2276/4885L3MBTL1 1064/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.