SCHEMBL18348585

SCHEMBL18348585

Cc1cc(C2(c3ccc(O)c(C)c3)c3ccccc3-c3cc4ccccc4cc32)ccc1O

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 4/20 0.80
▸ ESR2 Q92731 4/20 0.80
▸ MEN1 O00255 4/20 0.50
▸ KMT2A Q03164 4/20 0.50
▸ LMNA P02545 3/20 0.50
▸ MAPT P10636 3/20 0.50
▸ SMN1; SMN2 Q16637 2/20 0.50
▸ TDP1 Q9NUW8 2/20 0.50
▸ XBP1 P17861 1/20 0.50
▸ NPSR1 Q6W5P4 1/20 0.50
▸ POLB P06746 1/20 0.50
▸ L3MBTL1 Q9Y468 1/20 0.50
▸ KDM4E B2RXH2 1/20 0.42
▸ OPRK1 P41145 1/20 0.42
▸ NPC1 O15118 1/20 0.40
▸ HSP90AA1 P07900 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ TLR8 Q9NR97 1/20 0.37
▸ PDK2 Q15119 5/20 0.36
▸ PDE10A Q9Y233 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18386002 0.91 ESR1 (0.90) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL29358768 0.89 ESR1 (1.00) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL29450641 0.89 ESR1 (1.00) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL70957 0.89 ESR1 (1.00) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL15691554 0.88 ESR1 (0.97) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL12084149 0.86 ESR1 (0.93) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL18348578 0.85 ESR1 (0.56) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL12387987 0.85 ESR1 (0.90) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL17399575 0.84 ESR1 (0.88) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL10697013 0.84 ESR1 (0.88) ESR1ESR2MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9676956-B2 (Meth)acrylic resin composition, film, polarizing plate protective film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-06-13 — — US disclosed
US-9676956-B2 (Meth)acrylic resin composition, film, polarizing plate protective film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-06-13 — — US disclosed
US-20160376463-A1 (METH)ACRYLIC RESIN COMPOSITION, FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-12-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160376463-A1 (METH)ACRYLIC RESIN COMPOSITION, FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE METTL14, REV1, DRD2 ESR1 1484/4885ESR2 2146/4885MEN1 297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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