SCHEMBL1838828

SCHEMBL1838828

COc1ccc(CCCc2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 2/20 0.61
MEN1 O00255 1/20 0.54
NPC1 O15118 1/20 0.54
EPHX2 P34913 1/20 0.54
RAB9A P51151 1/20 0.54
KMT2A Q03164 1/20 0.54
NR1H4 Q96RI1 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
KCNH2 Q12809 1/20 0.53
ALOX15 P16050 2/20 0.53
ALDH1A1 P00352 2/20 0.53
LMNA P02545 1/20 0.53
APEX1 P27695 1/20 0.53
MAPK1 P28482 1/20 0.53
RECQL P46063 1/20 0.53
HSD17B10 Q99714 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
TAAR1 Q96RJ0 1/20 0.52
MAPT P10636 1/20 0.50
IGF1R P08069 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31573982 0.85 KCNH2 (0.67) NR1H4KCNH2LMNASIGMAR1
SCHEMBL244070 0.85 CALM1 (0.79) CALM1L3MBTL1ALOX15TDP1TAAR1
SCHEMBL3665016 0.83 MAPT (0.64) MEN1NPC1EPHX2RAB9AKMT2A
SCHEMBL78643 0.83 MAPT (0.64) MEN1NPC1EPHX2RAB9AKMT2A
SCHEMBL4254058 0.81 CALM1 (0.72) CALM1L3MBTL1ALOX15TDP1TAAR1
Fluoride SCHEMBL31538992 0.81 MAPT (0.62) MEN1NPC1EPHX2RAB9AKMT2A
SCHEMBL29007567 0.81 MMP13 (0.51) MEN1NPC1EPHX2RAB9AKMT2A
SCHEMBL28846374 0.80 MEN1 (0.47) CALM1MEN1NPC1EPHX2RAB9A
SCHEMBL4152967 0.80 GAA (0.64) MEN1NPC1EPHX2RAB9AKMT2A
SCHEMBL13439792 0.79 APP (0.72) NPC1RAB9AALDH1A1MAPTMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102406554-B Sunscreen compositions NEUTROGENA CORP. (US) 2014-10-01 CN claimed
CN-103221025-A Cosmetic composition for skin whitening comprising resveratrol DSM IP ASSETS BV 2013-07-24 CN claimed
CN-103221024-A Use of UV-filters for stabilizing resveratrol in topical cosmetic compositions DSM IP ASSETS BV 2013-07-24 CN claimed
CN-1902353-B Stabilized body care products, household products, textiles and fabrics CIBA SPEC CHEM CORP 2012-08-15 CN claimed
CN-102573776-A Tetrapeptides for brightening the skin EVONIK GOLDSCHMIDT GMBH 2012-07-11 CN claimed
CN-102448291-A Method for reducing sun damage of plants BASF SE 2012-05-09 CN claimed
EP-2320869-A1 SURFACTANT-FREE EMULSIONS WITH ANTI-AGING EFFECT, PRODUCTION THEREOF AND USE OF SAME HC Berlin Pharma Ag (DE) 2011-05-18 EP claimed
WO-2010012686-A1 SURFACTANT-FREE EMULSIONS WITH ANTI-AGING EFFECT, PRODUCTION THEREOF AND USE OF SAME HC BERLIN PHARMA AG (DE) 2010-02-04 WO claimed
CN-1902353-A Stabilized body care products, household products, textiles and fabrics CIBA SC HOLDING AG (CH) 2007-01-24 CN claimed
CN-1745740-A Diffractive colorants for cosmetics MERCK PATENT GMBH (DE) 2006-03-15 CN claimed
US-4686099-A Aerosol waterproof sunscreen compositions CHESEBROUGH-POND'S INC. 1987-08-11 US claimed
US-4683134-A HIGH VISCOSITY, GELS, ETHYL CELLULOSE, CROSSLINKED POLYACRYLIC ACID PALINCZAR VICTOR 1987-07-28 US claimed
US-20250000769-A1 SUNSCREEN OR DAILY CARE COMPOSITION COMPRISING BIS-ETHYLHEXYLOXYPHENOL METHOXYPHENYL TRIAZINE AND INORGANIC UV FILTERS BASF SE (DE) 2025-01-02 US disclosed
WO-2023237581-A1 NOVEL INSECT REPELLENT COMPOSITION UNIVERSITÄT FÜR BODENKULTUR WIEN (AT) 2023-12-14 WO disclosed
CN-116669687-A Antimicrobial compositions 科莱恩国际有限公司 2023-08-29 CN disclosed
WO-2023156768-A1 COMPOSITIONS FOR VITAMIN D PRODUCTION DR WELLER LIMITED (GB) 2023-08-24 WO disclosed
CN-1269714-A Use of esterquats as emulsifiers for producing preparations for dyeing keratin fibres HENKEL KOMMANDITYESELLSCHAFT A (DE) 2000-10-11 CN disclosed
CN-1198323-A Microstructure composition CIBA GEIGY AG (CH) 1998-11-11 CN disclosed
EP-0532725-A1 LIGHT SCREENING AGENT. GIVAUDAN ROURE INT (CH) 1993-03-24 EP disclosed
WO-1992017461-A1 LIGHT SCREENING AGENT GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1992-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250000769-A1 SUNSCREEN OR DAILY CARE COMPOSITION COMPRISING BIS-ETHYLHEXYLOXYPHENOL METHOXYPHENYL TRIAZINE AND INORGANIC UV FILTERS TYR, FHIT, POLR1C CALM1 4117/4885MEN1 1313/4885NPC1 2485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.