Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 8/20 | 0.52 |
| ▸ | PIM1 | P11309 | 7/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 7/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.52 |
| ▸ | PRKACA | P17612 | 6/20 | 0.52 |
| ▸ | GSK3B | P49841 | 6/20 | 0.52 |
| ▸ | CDK9 | P50750 | 5/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.52 |
| ▸ | HIPK2 | Q9H2X6 | 5/20 | 0.52 |
| ▸ | DAPK3 | O43293 | 4/20 | 0.52 |
| ▸ | CLK2 | P49760 | 4/20 | 0.52 |
| ▸ | CDK7 | P50613 | 4/20 | 0.52 |
| ▸ | PRKX | P51817 | 4/20 | 0.52 |
| ▸ | CDK8 | P49336 | 4/20 | 0.52 |
| ▸ | STK17A | Q9UEE5 | 4/20 | 0.52 |
| ▸ | FLT3 | P36888 | 3/20 | 0.52 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.52 |
| ▸ | MINK1 | Q8N4C8 | 3/20 | 0.52 |
| ▸ | CDK2 | P24941 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5618155 | 0.78 | TGFBR1 (0.71) | CDC7PIM1MAP4K4CLK4PRKACA | |
| SCHEMBL18392393 | 0.74 | SIRT2 (0.53) | PIM1PRKACAGSK3BCDK2PRKD3 | |
| SCHEMBL1043490 | 0.74 | CDC7 (0.82) | CDC7PIM1MAP4K4CLK4PRKACA | |
| SCHEMBL18392230 | 0.74 | DYRK1A (0.54) | PIM1MAP4K4CLK4GSK3BCDK9 | |
| SCHEMBL1050911 | 0.73 | TGFBR1 (0.60) | CDC7PIM1MAP4K4CLK4PRKACA | |
| SCHEMBL16705131 | 0.73 | FLT3 (0.67) | CDC7PIM1MAP4K4CLK4PRKACA | |
| SCHEMBL20846051 | 0.73 | RPS6KA5 (0.58) | CDC7PIM1MAP4K4CLK4PRKACA | |
| SCHEMBL858766 | 0.73 | CAMKK2 (0.64) | CDC7PIM1MAP4K4CLK4PRKACA | |
| SCHEMBL18392287 | 0.71 | PIM1 (0.52) | CDC7PIM1MAP4K4CLK4PRKACA | |
| SCHEMBL31097189 | 0.71 | AXL (0.60) | CDC7PIM1MAP4K4CLK4PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3319940-B1 | NEW INDOLE COMPOUNDS HAVING ANTIPROTOZOAL ACTIVITY AND ITS USE AS WELL AS METHODS FOR PRODUCING THE SAME | UNIV BRAUNSCHWEIG TECH (DE) | 2019-05-29 | — | — | EP | disclosed |
| US-10287271-B2 | Indole compounds having antiprotozoal activity and its use as well as methods for producing the same | TECHNISCHE UNIVERSITAET BRAUNSCHWEIG (DE) | 2019-05-14 | — | — | US | disclosed |
| US-10287271-B2 | Indole compounds having antiprotozoal activity and its use as well as methods for producing the same | TECHNISCHE UNIVERSITAET BRAUNSCHWEIG (DE) | 2019-05-14 | — | — | US | disclosed |
| US-20180194750-A1 | NEW INDOLE COMPOUNDS HAVING ANTIPROTOZOAL ACTIVITY AND ITS USE AS WELL AS METHODS FOR PRODUCING THE SAME | TECHNISCHE UNIVERSITAET BRAUNSCHWEIG (DE) | 2018-07-12 | — | — | US | disclosed |
| US-20180194750-A1 | NEW INDOLE COMPOUNDS HAVING ANTIPROTOZOAL ACTIVITY AND ITS USE AS WELL AS METHODS FOR PRODUCING THE SAME | TECHNISCHE UNIVERSITAET BRAUNSCHWEIG (DE) | 2018-07-12 | — | — | US | disclosed |
| US-20180194750-A1 | NEW INDOLE COMPOUNDS HAVING ANTIPROTOZOAL ACTIVITY AND ITS USE AS WELL AS METHODS FOR PRODUCING THE SAME | TECHNISCHE UNIVERSITAET BRAUNSCHWEIG (DE) | 2018-07-12 | — | — | US | disclosed |
| WO-2017008826-A1 | NEW INDOLE COMPOUNDS HAVING ANTIPROTOZOAL ACTIVITY AND ITS USE AS WELL AS METHODS FOR PRODUCING THE SAME | TECHNISCHE UNIVERSITAET BRAUNSCHWEIG (DE) | 2017-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180194750-A1 | NEW INDOLE COMPOUNDS HAVING ANTIPROTOZOAL ACTIVITY AND ITS USE AS WELL AS METHODS FOR PRODUCING THE SAME | IDO1, IDO2, INMT | CDC7 2247/4885PIM1 2093/4885MAP4K4 4139/4885 |
| US-10287271-B2 | Indole compounds having antiprotozoal activity and its use as well as methods for producing the same | IDO1, IDO2, INMT | CDC7 2139/4885PIM1 1922/4885MAP4K4 4057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.