Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | DNM2 | P50570 | 2/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.38 |
| ▸ | INSR | P06213 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | SUMO3 | P55854 | 1/20 | 0.38 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.38 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3320381 | 0.84 | KMT2A (0.46) | SLC2A1KMT2AMAPK13MAPK12MAPK11 | |
| SCHEMBL3316097 | 0.80 | MAPK13 (0.41) | SLC2A1HCAR3KMT2AMAPK13MAPK12 | |
| SCHEMBL10866005 | 0.80 | KMT2A (0.39) | SLC2A1HCAR3KMT2AMAPK13MAPK12 | |
| SCHEMBL3263843 | 0.80 | HRH4 (0.65) | SLC2A1HRH4 | |
| SCHEMBL31366117 | 0.79 | SUMO3 (0.39) | SLC2A1HCAR3KMT2AMAPK13MAPK12 | |
| SCHEMBL2163151 | 0.76 | ALDH1A1 (0.54) | SLC2A1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL369672 | 0.74 | MAPT (0.44) | HCAR3KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL7174094 | 0.74 | SLC2A1 (0.46) | SLC2A1HCAR3KMT2AMAPTMAPK1 | |
| SCHEMBL24741365 | 0.73 | MAPK13 (0.37) | SLC2A1KMT2AMAPK13MAPK12MAPK11 | |
| SCHEMBL3345160 | 0.72 | HCAR3 (0.46) | SLC2A1HCAR3HRH4KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7722893-B2 | Use of substitute 2,4-bis (alkylamino) pyrimidines or quinzolines as antimicrobials | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | claimed |
| US-20090269379-A1 | Material Having Antibacterial and Antifungal Properties | CIBA CORP. | 2009-10-29 | — | — | US | claimed |
| EP-1648524-B1 | USE OF SUBSTITUTED 2,4-BIS (ALKYLAMINO) PYRIMIDINES OR -QUINAZOLINES AS ANTIMICROBIALS | CIBA HOLDING INC (CH) | 2009-01-14 | — | — | EP | claimed |
| EP-1934277-A1 | MATERIAL HAVING ANTIBACTERIAL AND ANTIFUNGAL PROPERTIES | Ciba Holding Inc. (CH) | 2008-06-25 | — | — | EP | claimed |
| WO-2008046746-A2 | ACARICIDAL SYNTHETIC MATERIALS AND ARTICLES MADE THEREFROM | CIBA HOLDING INC. (CH) | 2008-04-24 | — | — | WO | claimed |
| WO-2007042416-A1 | MATERIAL HAVING ANTIBACTERIAL AND ANTIFUNGAL PROPERTIES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-04-19 | — | — | WO | claimed |
| US-20060188453-A1 | Use of substitute 2,4-bis (alkylamino)pyrimidines | CIBA SPECIALTY CHEMICALS CORP. | 2006-08-24 | — | — | US | claimed |
| EP-1648524-A2 | USE OF SUBSTITUTED 2,4-BIS (ALKYLAMINO) PYRIMIDINES OR -QUINAZOLINES AS ANTIMICROBIALS | Ciba SC Holding AG (CH) | 2006-04-26 | — | — | EP | claimed |
| WO-2005011758-A2 | USE OF SUBSTITUTED 2,4-BIS (ALKYLAMINO) PYRIMIDINES OR -QUINAZOLINES AS ANTIMICROBIALS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-02-10 | — | — | WO | claimed |
| US-20110150961-A1 | ANTI-INFECTIVE CATHETERS | ANGIOTECH INTERNATIONAL AG (CH) | 2011-06-23 | — | — | US | disclosed |
| EP-2315528-A2 | POLYOL DERIVED ANTI-MICROBIAL AGENTS AND COMPOSITIONS | BASF SE (DE) | 2011-05-04 | — | — | EP | disclosed |
| EP-2254640-A2 | ANTI-INFECTIVE CATHETERS | ANGIOTECH INTERNATIONAL AG (CH) | 2010-12-01 | — | — | EP | disclosed |
| US-7722893-B2 | Use of substitute 2,4-bis (alkylamino) pyrimidines or quinzolines as antimicrobials | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| US-7722893-B2 | Use of substitute 2,4-bis (alkylamino) pyrimidines or quinzolines as antimicrobials | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| US-20060188453-A1 | Use of substitute 2,4-bis (alkylamino)pyrimidines | CIBA SPECIALTY CHEMICALS CORP. | 2006-08-24 | — | — | US | disclosed |
| EP-1648524-A2 | USE OF SUBSTITUTED 2,4-BIS (ALKYLAMINO) PYRIMIDINES OR -QUINAZOLINES AS ANTIMICROBIALS | Ciba SC Holding AG (CH) | 2006-04-26 | — | — | EP | disclosed |
| EP-1648524-A2 | USE OF SUBSTITUTED 2,4-BIS (ALKYLAMINO) PYRIMIDINES OR -QUINAZOLINES AS ANTIMICROBIALS | Ciba SC Holding AG (CH) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005011758-A3 | USE OF SUBSTITUTED 2,4-BIS (ALKYLAMINO) PYRIMIDINES OR -QUINAZOLINES AS ANTIMICROBIALS | CIBA SC HOLDING AG (CH) | 2005-04-28 | — | — | WO | disclosed |
| WO-2005011758-A2 | USE OF SUBSTITUTED 2,4-BIS (ALKYLAMINO) PYRIMIDINES OR -QUINAZOLINES AS ANTIMICROBIALS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-02-10 | — | — | WO | disclosed |
| WO-2005011758-A2 | USE OF SUBSTITUTED 2,4-BIS (ALKYLAMINO) PYRIMIDINES OR -QUINAZOLINES AS ANTIMICROBIALS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110150961-A1 | ANTI-INFECTIVE CATHETERS | NACA, PUF60, POLR1C | SLC2A1 3200/4885DNM2 4391/4885HCAR3 1071/4885 |
| US-20090269379-A1 | Material Having Antibacterial and Antifungal Properties | POLR1C, NISCH, HSPH1 | SLC2A1 3247/4885DNM2 4417/4885HCAR3 676/4885 |
| US-20060188453-A1 | Use of substitute 2,4-bis (alkylamino)pyrimidines | PYM1, C1R, POLR1C | SLC2A1 2744/4885DNM2 1127/4885HCAR3 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.