SCHEMBL1840136

SCHEMBL1840136

C=CN1CCC(Cc2ccccc2)C1=O

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 4/20 0.55
ROCK2 O75116 1/20 0.43
DDB1 Q16531 1/20 0.42
CRBN Q96SW2 1/20 0.42
NPC1 O15118 1/20 0.40
ALDH1A1 P00352 1/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 1/20 0.40
MAOB P27338 1/20 0.40
SIGMAR1 Q99720 2/20 0.39
ALOX15 P16050 1/20 0.39
HTR1A P08908 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28434491 0.83 CHRNA7 (0.46) HSD11B1ALDH1A1
SCHEMBL5106732 0.79 HSD11B1 (0.59) HSD11B1ROCK2DDB1CRBNNPC1
SCHEMBL952662 0.76 FAAH (0.32)
SCHEMBL28942364 0.76 HSD11B1 (0.59) HSD11B1ROCK2DDB1CRBNNPC1
SCHEMBL5088875 0.76 HSD11B1 (0.59) HSD11B1ROCK2DDB1CRBNNPC1
SCHEMBL6733710 0.74 HSD11B1 (0.57) HSD11B1ROCK2DDB1CRBNALDH1A1
Hydrochloric Acid SCHEMBL5236156 0.74 HSD11B1 (0.57) HSD11B1ROCK2DDB1CRBNNPC1
SCHEMBL6484479 0.74 L3MBTL1 (0.40) ALDH1A1KMT2ASIGMAR1
SCHEMBL6654051 0.73 HSD11B1 (0.56) HSD11B1ROCK2DDB1CRBNNPC1
SCHEMBL6654054 0.73 HSD11B1 (0.56) HSD11B1ROCK2DDB1CRBNNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434362-B1 Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution TOMEI SANGYO KK (JP) 1995-03-22 EP claimed
EP-0433046-B1 Polymer-type polymerization initiator TOMEI SANGYO KK (JP) 1994-08-10 EP claimed
US-5206298-A GRAFT COPOLYMER, SOLUTION CONTAINING THE GRAFT COPOLYMER FOR TREATING CONTACT LENS, AND METHOD OF TREATING CONTACT LENS WITH THE SOLUTION AND MAKING HYDROPHILIC LENS SURFACE TOMEI SANGYO KABUSHIKI KAISHA (JP) 1993-04-27 US claimed
US-5134213-A N-Vinyllactam-Monoperoxyfumarate Terpolymer TOMEI SANGYO KABUSHIKI KAISHA (JP) 1992-07-28 US claimed
US-5082912-A For graft polymerization, surfactants TOMEI SANGYO KABUSHIKI KAISHA (JP) 1992-01-21 US claimed
EP-0434362-A1 Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution Tomei Sangyo Kabushiki Kaisha (JP) 1991-06-26 EP claimed
EP-0433046-A2 Polymer-type polymerization initiator Tomei Sangyo Kabushiki Kaisha (JP) 1991-06-19 EP claimed
US-4772359-A POLY-N-VINYLAMIDE AS DRAINAGE AID BASF AKTIENGESELLSCHAFT (DE) 1988-09-20 US claimed
EP-0249891-A1 Process for producing paper and cardboard BASF Aktiengesellschaft (DE) 1987-12-23 EP claimed
US-12252632-B2 Chemical-mechanical polishing composition, rinse composition, chemical- mechanical polishing method, and rinsing method ENTEGRIS, INC. (US) 2025-03-18 US disclosed
US-20250032510-A1 AMORPHOUS SOLID DISPERSION GANAXOLONE FORMULATION IMMEDICA PHARMA US INC. 2025-01-30 US disclosed
US-20230390305-A1 AMORPHOUS SOLID DISPERSION GANAXOLONE FORMULATION MARINUS PHARMACEUTICALS, INC. 2023-12-07 US disclosed
WO-2023060067-A1 AMORPHOUS SOLID DISPERSION GANAXOLONE FORMULATION MARINUS PHARMACEUTICALS, INC. (US) 2023-04-13 WO disclosed
US-20220372329-A1 CHEMICAL-MECHANICAL POLISHING COMPOSITION, RINSE COMPOSITION, CHEMICAL-MECHANICAL POLISHING METHOD, AND RINSING METHOD ENTEGRIS, INC. 2022-11-24 US disclosed
US-4711830-A Image recording material comprising photosensitive layer and recording layer on electroconductive base CANON KABUSHIKI KAISHA (JP) 1987-12-08 US disclosed
EP-0233039-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1987-08-19 EP disclosed
EP-0091039-B1 ANTI-FOULING AGENT Nitto Kasei Co., Ltd. (JP) 1986-10-01 EP disclosed
EP-0191645-A2 Recording medium and recording method by use thereof CANON KABUSHIKI KAISHA (JP) 1986-08-20 EP disclosed
US-4526932-A Copolymer containing N-coordinated triorganotin compound NITTO KASEI CO., LTD. (JP) 1985-07-02 US disclosed
EP-0091039-A2 Anti-fouling agent Nitto Kasei Co., Ltd. (JP) 1983-10-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250032510-A1 AMORPHOUS SOLID DISPERSION GANAXOLONE FORMULATION PYGB, GYS2, CYP21A2 HSD11B1 35/4885ROCK2 1102/4885DDB1 3493/4885
US-20230390305-A1 AMORPHOUS SOLID DISPERSION GANAXOLONE FORMULATION PYGB, GYS2, CYP21A2 HSD11B1 35/4885ROCK2 1102/4885DDB1 3493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.