Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | BLVRB | P30043 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28209807 | 0.78 | ALDH1A1 (0.36) | ALOX15ALDH1A1HSD17B10MEN1HTT | |
| SCHEMBL3316934 | 0.78 | PTGS2 (0.48) | ALOX15CA12CA1CA2CA9 | |
| SCHEMBL12228262 | 0.74 | MAPT (0.40) | ALOX15CA1CA2ALDH1A1HSD17B10 | |
| SCHEMBL20436095 | 0.74 | GLB1 (0.59) | ALOX15BRD4CA12CA2CA9 | |
| SCHEMBL11213671 | 0.73 | PTGS1 (0.53) | BRD4CA1CA2ALDH1A1HSD17B10 | |
| SCHEMBL19381131 | 0.73 | IDO1 (0.45) | — | |
| SCHEMBL14075868 | 0.73 | ALDH1A1 (0.33) | ALOX15ALDH1A1HSD17B10MEN1HTT | |
| SCHEMBL639211 | 0.73 | RAB9A (0.52) | ALOX15BRD4ALOX12ALDH1A1HSD17B10 | |
| SCHEMBL12458453 | 0.73 | MEN1 (0.40) | ALOX15ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL798232 | 0.73 | HSD17B10 (0.41) | ALDH1A1HSD17B10MEN1PDE4ABLVRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017159484-A1 | 2,4-DIAMINOPHENOL DERIVATIVE, AND AGENT FOR INHIBITING AGGREGATION OF TAU AND/OR AMYLOID β | 学校法人同志社 | 2017-09-21 | — | — | WO | disclosed |
| EP-2401392-B1 | SOLUTION PHASE HOMOGENEOUS ASSAYS | BECKMAN COULTER INC (US) | 2017-01-25 | — | — | EP | disclosed |