Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 5/20 | 0.45 |
| ▸ | BLM | P54132 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12228262 | 0.80 | MAPT (0.40) | PTGS2PTGS1POLBBLMKDM4E | |
| SCHEMBL12206647 | 0.80 | MAPT (0.58) | POLBBLMKDM4EMEN1KMT2A | |
| SCHEMBL798232 | 0.78 | HSD17B10 (0.41) | KDM4EMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL10208077 | 0.78 | HSD17B10 (0.50) | PTGS2PTGS1POLBBLMKDM4E | |
| SCHEMBL11213671 | 0.78 | PTGS1 (0.53) | PTGS2PTGS1POLBMEN1KMT2A | |
| SCHEMBL639211 | 0.78 | RAB9A (0.52) | KDM4EMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL13268128 | 0.78 | ALDH1A1 (0.37) | PTGS2PTGS1BLMKDM4EMEN1 | |
| SCHEMBL10208078 | 0.78 | ALDH1A1 (0.37) | PTGS2PTGS1BLMMEN1KMT2A | |
| SCHEMBL21087428 | 0.78 | TSHR (0.46) | PTGS1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL18403872 | 0.78 | ALOX15 (0.50) | PTGS2PTGS1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108586474-A | Simultaneously [2,3-b] indole derivatives and its preparation and application of benzo [5,6] [1,4] Dioxin | 福州大学 | 2018-09-28 | — | — | CN | disclosed |
| EP-3257887-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2017-12-20 | — | — | EP | disclosed |
| US-7723444-B2 | retarding the curing of the epoxy resin by adjusting an amount of the retarder while curing in presence of a curing accelerator cation phosphorus compound; used for semiconductor encapsulation; providing latency; storage stability; resist to soldering without forming cracks by the soldering | SUMITOMO BAKELITE CO., LTD. (JP) | 2010-05-25 | — | — | US | disclosed |
| US-7662979-B2 | cyanation; dopamine autoreceptor agonists and partial agonists at postsynaptic dopamine D2 receptor; for treating dopaminergic disorders such as schizophrenia, schizoaffective disorder, Parkinson's disease, Tourette's syndrome, hyperprolactinemia, and drug addiction | WYETH (US) | 2010-02-16 | — | — | US | disclosed |
| US-20060189721-A1 | retarding the curing of the epoxy resin by adjusting an amount of the retarder while curing in presence of a curing accelerator cation phosphorus compound; used for semiconductor encapsulation; providing latency; storage stability; resist to soldering without forming cracks by the soldering | SUMITOMO BAKELITE CO., LTD. (JP) | 2006-08-24 | — | — | US | disclosed |
| US-4011181-A | POLYURETHANE FOAMS CONTAINING STANNOUS CATECHOL DERIVATIVES | OLIN CORPORATION (US) | 1977-03-08 | — | — | US | disclosed |