Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | RORA | P35398 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | RORB | Q92753 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28283584 | 0.83 | BRPF1 (0.46) | TLR8MAPTGPR84MEN1KMT2A | |
| SCHEMBL28870713 | 0.81 | BRPF1 (0.45) | TLR8MAPTGPR84MEN1KMT2A | |
| SCHEMBL287263 | 0.81 | OXER1 (0.54) | GPR84OXER1 | |
| SCHEMBL3699735 | 0.81 | OXER1 (0.54) | GPR84OXER1 | |
| SCHEMBL16452837 | 0.81 | MAPT (0.50) | MAPTRXFP1LMNATP53THRB | |
| SCHEMBL28932571 | 0.80 | DHFR (0.45) | TLR8PPARGPPARATP53MEN1 | |
| SCHEMBL28223276 | 0.80 | OXER1 (0.53) | OXER1 | |
| SCHEMBL1315631 | 0.79 | HTR2A (0.42) | TLR8GPR84LMNATP53MEN1 | |
| SCHEMBL3696937 | 0.79 | OXER1 (0.54) | GPR84OXER1 | |
| SCHEMBL18407425 | 0.78 | GPR84 (0.47) | TLR8MAPTGPR84MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717091-B | Indole derivatives and preparation method and application thereof | 南京医科大学 | 2023-03-10 | — | — | CN | disclosed |