Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14108149 | 0.92 | ADORA3 (0.51) | ADORA3KMT2ASMN1; SMN2ESR1HIF1A | |
| SCHEMBL12404386 | 0.86 | KMT2A (0.48) | ADORA3KMT2AESR1BACE1NPC1 | |
| SCHEMBL12919554 | 0.86 | KMT2A (0.48) | ADORA3KMT2AESR1BACE1NPC1 | |
| SCHEMBL13144068 | 0.85 | MAPT (0.49) | ADORA3KMT2ABACE1NPC1RAB9A | |
| SCHEMBL16158986 | 0.84 | ADORA3 (0.41) | ADORA3KMT2AESR1BACE1LMNA | |
| SCHEMBL23968910 | 0.82 | ESR2 (0.57) | ADORA3KMT2AESR1BACE1GRIN1 | |
| SCHEMBL14877709 | 0.82 | KDM4E (0.47) | ADORA3KMT2ASMN1; SMN2ESR1BACE1 | |
| SCHEMBL16488963 | 0.82 | KMT2A (0.51) | ADORA3KMT2AESR1BACE1NPC1 | |
| SCHEMBL12221853 | 0.82 | FAAH (0.48) | ADORA3KMT2ASMN1; SMN2BACE1NPC1 | |
| SCHEMBL19194913 | 0.82 | KMT2A (0.51) | ADORA3KMT2AESR1BACE1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080008952-A1 | Organophotoreceptor and electrophotographic imaging apparatus including the organophotoreceptor | SAMSUNG ELECTRONICS CO., LTD. | 2008-01-10 | — | — | US | disclosed |