Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20867240 | 0.88 | RECQL (0.39) | PIK3CAPIK3CDPIK3CBPIK3R1ALDH1A1 | |
| SCHEMBL18412848 | 0.88 | PIK3CA (0.42) | PIK3CAPIK3CDPIK3CBPIK3R1ALDH1A1 | |
| SCHEMBL18412822 | 0.84 | PIK3CA (0.46) | PIK3CAPIK3CDPIK3CBPIK3R1ALDH1A1 | |
| SCHEMBL20098203 | 0.84 | ALDH1A1 (0.47) | PIK3CAALDH1A1KDM4EGAAMAPT | |
| SCHEMBL18412875 | 0.82 | L3MBTL1 (0.41) | PIK3CAPIK3CDPIK3CBALDH1A1KDM4E | |
| SCHEMBL18412861 | 0.81 | PIK3CA (0.40) | PIK3CAPIK3CDPIK3CBPIK3R1ALDH1A1 | |
| SCHEMBL18412898 | 0.80 | PIK3CA (0.39) | PIK3CAPIK3CDPIK3CBPIK3R1ALDH1A1 | |
| SCHEMBL18412850 | 0.80 | PIK3CA (0.39) | PIK3CAPIK3CDPIK3CBPIK3R1ALDH1A1 | |
| SCHEMBL18412878 | 0.79 | PIK3CA (0.38) | PIK3CAPIK3CDPIK3CBPIK3R1ALDH1A1 | |
| SCHEMBL20097527 | 0.77 | PIK3CA (0.37) | PIK3CAPIK3CDPIK3CBPIK3R1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957281-B2 | Benzodiazepine derivatives as RSV inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2018-05-01 | — | — | US | disclosed |
| US-20170022221-A1 | BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2017-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022221-A1 | BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | GABRA5, GABRA1, GABBR2 | PIK3CA 2807/4885PIK3CD 2856/4885PIK3CB 2664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.