Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.71 |
| ▸ | XDH | P47989 | 3/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | KDM1A | O60341 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dihydrobiochanin A SCHEMBL30217535 | 0.85 | ALOX12 (0.67) | PTPN1XDHCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL30217542 | 0.85 | PTPN1 (0.57) | PTPN1CYP1A1CYP1A2CYP1B1TP53 | |
| SCHEMBL17963719 | 0.85 | PTPN1 (0.57) | PTPN1CYP1A1CYP1A2CYP1B1TP53 | |
| SCHEMBL29559295 | 0.84 | ALOX12 (0.56) | PTPN1XDHCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL678189 | 0.82 | ALOX12 (0.65) | PTPN1CYP1A1CYP1A2CYP1B1TP53 | |
| SCHEMBL12825176 | 0.82 | ALOX12 (0.65) | PTPN1CYP1A1CYP1A2CYP1B1TP53 | |
| SCHEMBL29412620 | 0.82 | ALOX12 (0.65) | PTPN1CYP1A1CYP1A2CYP1B1TP53 | |
| SCHEMBL13640753 | 0.81 | PTPN1 (0.56) | PTPN1CYP1A1CYP1A2CYP1B1CYP3A4 | |
| SCHEMBL572085 | 0.81 | PTPN1 (0.67) | PTPN1XDHCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL31238344 | 0.81 | PTPN1 (0.56) | PTPN1XDHCYP1A1CYP1A2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2842428-B1 | Oral composition | SYMRISE AG (DE) | 2018-08-08 | — | — | EP | disclosed |
| EP-1977655-B1 | Aroma compositions of alkamides with hesperetin and/or 4-hydroxydihydrochalkones and their salts for reinforcing sweet sensory impressions | SYMRISE AG (DE) | 2011-05-18 | — | — | EP | disclosed |
| EP-1977655-A1 | Aroma compositions of alkamides with hesperetin and/or 4-hydroxydihydrochalkones and their salts for reinforcing sweet sensory impressions | Symrise GmbH & Co. KG (DE) | 2008-10-08 | — | — | EP | disclosed |
| EP-1977655-A1 | Aroma compositions of alkamides with hesperetin and/or 4-hydroxydihydrochalkones and their salts for reinforcing sweet sensory impressions | Symrise GmbH & Co. KG (DE) | 2008-10-08 | — | — | EP | disclosed |
| US-20080242740-A1 | AROMA COMPOSITIONS OF ALKAMIDES WITH HESPERETIN AND/OR 4-HYDROXYDIHYDROCHALCONES AND SALTS THEREOF FOR ENHANCING SWEET SENSORY IMPRESSIONS | SYMRISE GMBH & CO. KG (DE) | 2008-10-02 | — | — | US | disclosed |
| US-20080242740-A1 | AROMA COMPOSITIONS OF ALKAMIDES WITH HESPERETIN AND/OR 4-HYDROXYDIHYDROCHALCONES AND SALTS THEREOF FOR ENHANCING SWEET SENSORY IMPRESSIONS | SYMRISE GMBH & CO. KG (DE) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242740-A1 | AROMA COMPOSITIONS OF ALKAMIDES WITH HESPERETIN AND/OR 4-HYDROXYDIHYDROCHALCONES AND SALTS THEREOF FOR ENHANCING SWEET SENSORY IMPRESSIONS | TAS2R5, TAS2R20, TAS2R40 | PTPN1 3946/4885XDH 3910/4885CYP1A1 1248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.