Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL430012 | 0.85 | SIGMAR1 (0.54) | MEN1KMT2ASIGMAR1AOC3 | |
| SCHEMBL1478014 | 0.83 | SIGMAR1 (0.52) | MEN1KMT2ASIGMAR1 | |
| SCHEMBL9560040 | 0.81 | SIGMAR1 (0.55) | MEN1KMT2ASIGMAR1 | |
| SCHEMBL9245700 | 0.81 | SIGMAR1 (0.55) | MEN1KMT2ASIGMAR1 | |
| SCHEMBL6249417 | 0.81 | SIGMAR1 (0.55) | MEN1KMT2ASIGMAR1 | |
| SCHEMBL448516 | 0.80 | GPR52 (0.55) | GPR52ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL106847 | 0.80 | GPR52 (0.55) | GPR52ALDH1A1HPGDALOX15ALOX12 | |
| Propene SCHEMBL4543632 | 0.78 | ALDH1A1 (0.42) | GPR52ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL205556 | 0.78 | ALDH1A1 (0.52) | GPR52ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL7762166 | 0.78 | GPR52 (0.57) | GPR52ALDH1A1HPGDALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1411 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601669-B | Tire with a composition comprising an ethylene-rich elastomer, a peroxide and a specific acrylate derivative | 米其林集团总公司 | 2022-12-16 | — | — | CN | claimed |
| EP-3840960-A1 | TYRE HAVING A COMPOSITION COMPRISING AN ETHYLENE-RICH ELASTOMER, A PEROXIDE AND A SPECIFIC ACRYLATE DERIVATIVE | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2021-06-30 | — | — | EP | claimed |
| CN-107912040-B | Pyrrolidine amide compounds as histone demethylase inhibitors | 基因泰克公司 | 2021-04-06 | — | — | CN | claimed |
| CN-112601669-A | Tire with a composition comprising an ethylene-rich elastomer, a peroxide and a specific acrylate derivative | 米其林集团总公司 | 2021-04-02 | — | — | CN | claimed |
| WO-2020038761-A1 | TYRE HAVING A COMPOSITION COMPRISING AN ETHYLENE-RICH ELASTOMER, A PEROXIDE AND A SPECIFIC ACRYLATE DERIVATIVE | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2020-02-27 | — | — | WO | claimed |
| CN-109096337-B | A kind of phospha indole derivatives, benzo phospha indole derivatives and preparation method thereof | 苏州大学 | 2019-11-22 | — | — | CN | claimed |
| WO-2019153216-A1 | SUBSTITUTED ARYLAMINO ALCOHOL COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 北京梅尔森医药技术开发有限公司 | 2019-08-15 | — | — | WO | claimed |
| CN-108299279-A | Substituted aryl amine alcohol compound and its preparation method and application | 北京梅尔森医药技术开发有限公司 | 2018-07-20 | — | — | CN | claimed |
| US-10022354-B2 | Pyrrolidine amide compounds as histone demethylase inhibitors | GENENTECH, INC. (US) | 2018-07-17 | — | — | US | claimed |
| EP-3331890-A1 | PROTECTED ORGANOBORONIC ACIDS WITH TUNABLE REACTIVITY, AND METHODS OF USE THEREOF | The Board of Trustees of the University of Illionis (US) | 2018-06-13 | — | — | EP | claimed |
| WO-1992003131-A1 | USE OF HETEROCYCLIC AMINO-ALCOHOL COMPOUNDS FOR TREATMENT OF CNS DISEASES | G.D. SEARLE & CO. (US) | 1992-03-05 | — | — | WO | claimed |
| US-5049161-A | Mixtures of dicyanobenzanthrone compounds | CIBA-GEIGY CORPORATION (US) | 1991-09-17 | — | — | US | claimed |
| EP-0181292-B1 | PROCESS FOR THE CONTINUOUS TRICHROMATIC DYEING OF SYNTHETIC POLYAMIDE MATERIALS | CIBA-GEIGY AG (CH) | 1990-07-25 | — | — | EP | claimed |
| EP-0346277-A1 | Mixtures of dicyanbenzathrone compounds | CIBA-GEIGY AG (CH) | 1989-12-13 | — | — | EP | claimed |
| EP-0284952-A2 | Substituted propylamines | BAYER AG (DE) | 1988-10-05 | — | — | EP | claimed |
| US-4338330-A | HYPOTENSIVE AGENTS | CONTINENTAL PHARMA (BE) | 1982-07-06 | — | — | US | claimed |
| US-4101579-A | Phenethanolamine ethers | ALLEN & HANBURYS LIMITED (GB) | 1978-07-18 | — | — | US | claimed |
| US-4049797-A | 1-PHENOXY-2-HYDROXY-3-AMINO-PROPANE-SUGAR COMPOUND | CIBA-GEIGY CORPORATION (US) | 1977-09-20 | — | — | US | claimed |
| US-4001421-A | THIAZOLE CARDIOVASCULAR AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-01-04 | — | — | US | claimed |
| US-3978041-A | CARDIAC INSUFFICIENCY | CIBA-GEIGY CORPORATION (US) | 1976-08-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10022354-B2 | Pyrrolidine amide compounds as histone demethylase inhibitors | KDM5A, KDM5C, KDM1B | GPR52 3203/4885ALDH1A1 1149/4885HPGD 1121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.