Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 12/20 | 0.64 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.34 |
| ▸ | CDC7 | O00311 | 3/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434855 | 0.89 | SLC40A1 (0.62) | SLC40A1 | |
| SCHEMBL18434826 | 0.79 | SLC40A1 (0.63) | SLC40A1GRM4CDC7ROCK2PIM1 | |
| SCHEMBL18434824 | 0.79 | SLC40A1 (0.63) | SLC40A1 | |
| SCHEMBL11973003 | 0.78 | SLC40A1 (1.00) | SLC40A1 | |
| SCHEMBL18434500 | 0.75 | SLC40A1 (0.63) | SLC40A1 | |
| SCHEMBL18434654 | 0.74 | SLC40A1 (0.58) | SLC40A1 | |
| SCHEMBL18434664 | 0.73 | SLC40A1 (0.55) | SLC40A1 | |
| SCHEMBL18434472 | 0.73 | KDM4E (0.39) | SLC40A1 | |
| SCHEMBL12475058 | 0.73 | SLC40A1 (0.55) | SLC40A1 | |
| SCHEMBL18434412 | 0.73 | SLC40A1 (0.55) | SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |