Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 17/20 | 0.62 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434469 | 0.89 | SLC40A1 (0.64) | SLC40A1 | |
| SCHEMBL18434824 | 0.82 | SLC40A1 (0.63) | SLC40A1 | |
| SCHEMBL18434500 | 0.82 | SLC40A1 (0.63) | SLC40A1CYP2C19 | |
| SCHEMBL18434697 | 0.77 | SLC40A1 (0.67) | SLC40A1 | |
| SCHEMBL11972885 | 0.77 | SLC40A1 (1.00) | SLC40A1 | |
| SCHEMBL18434485 | 0.76 | SLC40A1 (0.67) | SLC40A1TDP1 | |
| SCHEMBL18434472 | 0.75 | KDM4E (0.39) | SLC40A1TDP1 | |
| SCHEMBL18434664 | 0.75 | SLC40A1 (0.55) | SLC40A1TDP1 | |
| SCHEMBL18434412 | 0.75 | SLC40A1 (0.55) | SLC40A1TDP1 | |
| SCHEMBL12475058 | 0.75 | SLC40A1 (0.55) | SLC40A1CYP2D6CYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |